Results 91 to 100 of about 971,698 (313)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Otolaryngology residency program factors associated with female resident representation

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery
Objective Female representation in the field of otolaryngology is lacking. Residency is the first point at which medical school graduates specialize in a chosen field and thus represents an opportunity to recruit and train more female otolaryngologists ...
Julia E. Canick   +4 more
doaj   +1 more source

Women are from Venus, Men are from Mars: But Do the Financial Markets Know It?

open access: yes, 2014
Available online on the publisher's website: http://www.accessecon.com/Pubs/EB/2014/Volume34/EB-14-V34-I1-P56.pdfInternational audienceAlthough existing research has documented in very wide and detailed terms the impact of the presence of female ...
Charles, Amélie, Redor, Etienne
core   +1 more source

Standard Chartered Bank: Women on Corporate Boards in India 2010 [PDF]

open access: yes, 2010
This first Standard Chartered Bank: Women on Corporate Boards in India 2010 report looks at the representation of women on the boards of India's leading companies on the Bombay Stock Exchange (BSE-100) .
Banerji, A.   +3 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Gender Aspects of the Professionalism of Female Teachers in Ukraine within the Context of Expanding Employment Rights at the Beginning of the 20th Century

open access: yesКиївські історичні студії
Motherhood for women remains a factor causing gender inequality in the labor market. This study examines the gender aspects of the professionalism of female teachers in Ukraine within the context of the expansion of their employment rights at the turn of
Oksana Drach
doaj   +1 more source

The Round Table on Women's Issues snapshot project: the status of women in libraries internationally [PDF]

open access: yes, 2002
This project was commissioned by the Round Table on Women's Issues (RTWI) at the 66th IFLA conference. The Round Table on Women's Issues is a sub-division of IFLA which concerns itself extensively with questions and issues that have special relevance for
Gannon-Leary, Pat, Parker, Sandra
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy