Results 101 to 110 of about 405,311 (310)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Who gets the Carrot and Who gets the Stick? Evidence of Gender Disparities in Executive Remuneration [PDF]

open access: yes
This paper offers a new explanation of the gender pay gap in leadership positions by examining the relationship between managerial bonuses and company performance.
Haslam, S.A.   +4 more
core   +1 more source

Board structure, ownership structure and firm performance: A study of New Zealand listed-firms [PDF]

open access: yes, 2012
This paper investigates the role of board structure and the effect of ownership structures on firm performance in New Zealand's listed firms. Several studies, the majority from the U.S., U.K.
Fauzi, Fitriya, Locke, Stuart
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Why So Few Women on Boards of Directors? Empirical Evidence from Danish Companies 1997-2007 [PDF]

open access: yes, 2013
This paper analyzes the determinants of women on the boards of directors based on a panel sample of all Danish companies in the private sector with more than 50 employees.
Parrotta, Pierpaolo, Smith, Nina
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

BOARD GENDER DIVERSITY AND ITS IMPACT ON FIRM VALUE AND FINANCIAL RISK

open access: yesMIX: Jurnal Ilmiah Manajemen, 2019
One of the things that can be done to maximize firm value is by having a board of directors with diverse characteristics. Gender diversity in the firm’s board of directors can bring a positive impact to the firm.
yunia panjaitan
doaj   +1 more source

Identity, Power, and Hiring in a Feminized Profession [PDF]

open access: yes, 1985
published or submitted for ...
Ivy, Barbara A.
core  

Occupational safety and health practice: a study at rubber manufacturing industry by using hirarc [PDF]

open access: yes, 2020
Occupational Safety and Health Act (OSHA) is a discipline with broad scope involving many specialized fields. The definition of safety is the state of being ‘safe’, condition of being protected against physical, social, spiritual, financial, political ...
Ahmad Jais, Mohamad Harizat   +5 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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