Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Female Genital Tract Host Factors and Tenofovir and Lamivudine Active Metabolites. [PDF]
Lantz AM +7 more
europepmc +1 more source
Interaction of Human Sperm Acrosomal Proteinase with Human seminal Plasma Proteinase Inhibitors [PDF]
Fink, Edwin +4 more
core +1 more source
Anaerobe‐Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition
ABSTRACT Background Genital microbiome dysbiosis is an important risk factor for the sexual acquisition of human immunodeficiency virus (HIV) in both the male and female genital tracts. The vaginal, penile and urethral mucosae are distinct microenvironments with characteristic microbiome compositions.
Shirley Constable +6 more
wiley +1 more source
Long-term survival outcomes of female genital tract rhabdomyosarcoma in children, adolescents and young adults at a national rare disease diagnosis and treatment center in China. [PDF]
Zheng J +6 more
europepmc +1 more source
Tenofovir, Interferon Pathways, and Mucosal Immunity: Implications for People Living With HIV
ABSTRACT Background Antiretroviral therapy (ART) suppresses HIV replication and protects people living with HIV (PLWH) from progressing to AIDS. However, despite ART, many PLWH experience chronic immune activation, which contributes to premature aging and non‐AIDS‐related comorbidities. One reason for this chronic immune activation (CIA) is HIV and its
Florian Hladik +5 more
wiley +1 more source
Exploring the female genital tract mycobiome in young South African women using metaproteomics. [PDF]
Gangiah TK +16 more
europepmc +1 more source
ABSTRACT The black soldier fly (BSF; Hermetia illucens) is rapidly emerging as a model for evolutionary biology and insect biotechnology. Although larval biology has been extensively characterised, the reproductive biology of adults remains comparatively understudied.
Noah B. Lemke, Nalini Puniamoorthy
wiley +1 more source
Cytokine concentration and T cell subsets in the female genital tract in the presence of bacterial vaginosis and <i>Trichomonas vaginalis</i>. [PDF]
Young MR +7 more
europepmc +1 more source
Macroscopical and histological characterization of the perineal membrane and deep perineal pouch
The existence of the deep transverse perineal muscle remains controversial. While the macroscopic appearance of the tissue in the deep perineal pouch differs between men and women, the differences in the histological composition of this fibromuscular plate is still unclear.
Morten Kampelmann +3 more
wiley +1 more source

