Results 91 to 100 of about 107,434 (351)

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

A new genus for the Neotropical species of Aesalus Fabricius, with descriptions of eight new species (Coleoptera: Lucanidae: Aesalinae) [PDF]

open access: yes, 2013
The Neotropical members of the genus Aesalus Fabricius (Coleoptera: Lucanidae: Aesalinae) are transferred to a new genus, Trogellus, due to their morphological dissimilarity and molecular divergence from the Old World species of Aesalus, and the new ...
Paulsen, Matthew J.
core  

Flutamide-induced hypospadias in rats: A critical assessment. [PDF]

open access: yes, 2017
This paper provides the first detailed description of flutamide-induced hypospadias in the rat based upon wholemount, histologic, three-dimensional reconstruction, scanning electron microscopic, and immunocytochemical analysis.
Baskin, Laurence   +4 more
core   +2 more sources

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

Brain Gender and Transsexualism [PDF]

open access: yes, 2007
Research by neuroscientists suggests there is a distinction in the BSTc area of the brain between males and females. In transsexual females, those considered male at birth, but who had a strong conviction that they were female, the BSTc region appears to
Kilty, Madeline
core  

The Trichoptera of Panama XIV. New species of microcaddisflies (Trichoptera: Hydroptilidae) from Omar Torrijos Herrera National Park [PDF]

open access: yes, 2020
. In 2017, a new project was begun to assess the biodiversity of national parks and forest reserves in the Republic of Panama. Designated “Proyecto Sistema de Producción Sostenible Conservación de la Biodiversidad (PSPSCB)”, this project is managed by ...
Armitage, Brian J., Harris, Steven C.
core   +2 more sources

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

open access: yesAdvanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez   +8 more
wiley   +1 more source

A New Record of the Genus Lepidogma Meyrick, 1890 from Turkey with Description of the Genitalia (Lepidoptera: Pyralidae, Epipaschiinae)

open access: yesSHILAP, 2019
Lepidogma wiltshirei Amsel, 1949 is new discovered in the Turkish fauna. The female genitalia of the species are described for the first time, the male genitalia are re-described and, the pictures of the species are illustrated.
A. Akin, E. Seven, A. Çakir
doaj   +1 more source

West Indian species of Beameromyia Martin (Diptera: Asilidae) [PDF]

open access: yes, 2011
The West Indian species of Beameromyia Martin are reviewed. Four new species are described, and Beameromyia insulara Martin and B. cubensis (Bigot) are redescribed.
Scarbrough, Aubrey G.
core  

Duplicated female receptacle organs for traumatic insemination in the tropical bed bug Cimex hemipterus: adaptive variation or malformation? [PDF]

open access: yes, 2014
During mating, male bed bugs (Cimicidae) pierce the female abdomen to inject sperm using their needle-like genitalia. Females evolved specialized paragenital organs (the spermalege and associated structures) to receive traumatically injected ejaculates ...
Kamimura, Yoshitaka   +2 more
core   +3 more sources

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