Results 241 to 250 of about 193,162 (347)
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu +8 more
wiley +1 more source
Clinical practice perspectives on adipose-derived stem cells and platelet-rich plasma for female infertility treatments. [PDF]
Merhi Z.
europepmc +1 more source
This study presents an ultrasound‐responsive hydrogel (MCF@CA) that co‐delivers a neuropeptide (CGRP) and a ROS‐scavenging manganese porphyrin to diabetic wounds. The system restores neuro‐immune communication, reprograms macrophages toward an anti‐inflammatory phenotype, and clears excess ROS, thereby accelerating wound closure and promoting mature ...
Mofan Li +9 more
wiley +1 more source
Commentary: Dietary index for gut microbiota and its inverse association with female infertility: evidence from NHANES 2013-2018. [PDF]
Du R, Jin B, Liu T, Zhang P.
europepmc +1 more source
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
Absence of CDK12 in oocyte leads to female infertility. [PDF]
Jansova D +9 more
europepmc +1 more source

