Results 91 to 100 of about 1,792,054 (353)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Diurnal and Seasonal Activity Patterns of Drosophilid Species (Diptera: Drosophilidae) Present in Blackberry Agroecosystems With a Focus on Spotted-Wing Drosophila [PDF]

open access: yes, 2020
Drosophilid species with different life histories have been shown to exhibit similar behavioral patterns related to locating and utilizing resources such as hosts, mates, and food sources.
Burrack, Hannah   +1 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Design Requirements of a Novel Wearable System for Safety and Performance Monitoring in Women’s Soccer

open access: yesApplied Sciences
Female soccer is rapidly becoming a widely practiced sport at different levels: this opens up a new demand for systems meant to protect athletes from head impacts or to monitor their effects.
Denise Bentivoglio   +4 more
doaj   +1 more source

Gender, poverty, and nonfarm employment in Ghana and Uganda [PDF]

open access: yes
The authors provide evidence that women's non-farm activities help reduce poverty in two economically and culturally different countries, Ghana and Uganda.
Canagarajah, Sudharshan   +1 more
core  

Pacific Hagfish, Eptatretus stouti, and Black Hagfish, E. deani: The Oregon Fishery and Port Sampling Observations, 1988-92 [PDF]

open access: yes, 1993
In 1988, the Oregon Department of Fish and Wildlife began sampling and monitoring the development of a new fishery for Pacific hagfish, Eptatretus stouti, and black hagfish, E. deani.
Barss, William H.
core  

Comparison of Abstinence and Coital Frequency Between 2 Natural Methods of Family Planning [PDF]

open access: yes, 2014
Introduction The length of periodic abstinence, due to overestimation of the fertile phase of the menstrual cycle, is often a cause for dissatisfaction, discontinuation, and user error with natural family planning (NFP) methods.
Arévalo   +25 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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