Results 51 to 60 of about 53,821 (261)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

“Mais do que objetos”: duas lideranças e pesquisadoras Tupinambá em busca dos seus “ancestrais” na França

open access: yesArgumentos
Through the experiences of Glicéria, Jéssica Tupinambá and Nathalie Pavelic, the article highlights the importance of access to the usurped cultural heritage of indigenous peoples to revitalize the ancestral memory of indigenous ...
Glicéria Tupinambá   +2 more
doaj   +1 more source

Efficacy of tennis elbow (Epicondylitis humeri radialis) treatment in CBR "PRAXIS".

open access: yesBiomolecules & Biomedicine, 2009
Tennis elbow (Epicondylitis humeri radialis) is the most frequent reason that patients with elbow pain report to a physician. The exact cause of elbow pain is still unclear. However, it is certainly causally connected with connective intersection between
Džemal Pecar, Dijana Avdić
doaj   +1 more source

“The Identity Problem” in Prenatal Testing

open access: yesVoices in Bioethics, 2020
GENETICIST You've already specified blue eyes, dark hair and fair skin. I have taken the liberty of eradicating any potentially prejudicial conditions – premature baldness, myopia, alcoholism and addictive susceptibility, propensity for violence ...
Nina Beguš
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid–Induced InjurySummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2018
Background & Aims: Ileal bile acid absorption is mediated by uptake via the apical sodium-dependent bile acid transporter (ASBT), and export via the basolateral heteromeric organic solute transporter α-β (OSTα-OSTβ).
Courtney B. Ferrebee   +8 more
doaj   +1 more source

Reverse electromechanical modelling of diastolic dysfunction in spontaneous hypertensive rat after sacubitril/valsartan therapy

open access: yesESC Heart Failure, 2020
Aims Hypertension is a significant risk for the development of left ventricular hypertrophy, diastolic dysfunction, followed by heart failure and sudden cardiac death.
Yen‐Ling Sung   +6 more
doaj   +1 more source

The Anchorage, Alaska Municipal Pretrial Diversion Program: Initial Outcome Assessment [PDF]

open access: yes, 2016
This report provides an initial outcome assessment of the Anchorage Municipal Pretrial Diversion Program, a voluntary program aimed at diverting first-time offenders in certain criminal and traffic cases from traditional case processing, with successful
Lepage, Cory R., May, Jeff D.
core  

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

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