Results 41 to 50 of about 185,269 (263)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Female Sex Work Industry in a District of India in the Context of HIV Prevention

AIDS Research and Treatment, 2012
HIV prevalence in India remains high among female sex workers. This paper presents the main findings of a qualitative study of the modes of operation of female sex work in Belgaum district, Karnataka, India, incorporating fifty interviews with sex ...
Raluca Buzdugan, Shiva S. Halli, Jyoti M. Hiremath, Krishnamurthy Jayanna, T. Raghavendra, Stephen Moses, James Blanchard, Graham Scambler, Frances Cowan   +8 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Increasing age and duration of sex work among female sex workers in South Africa and implications for HIV incidence estimation: Bayesian evidence synthesis and simulation exercise

Infectious Disease Modelling
Introduction: In sub-Saharan Africa, accurate estimates of the HIV epidemic in female sex workers are crucial for effective prevention and care strategies. These estimates are typically derived from mathematical models that assume certain demographic and
Nanina Anderegg, Mariette Slabbert, Kholi Buthelezi, Leigh F. Johnson   +3 more
doaj   +1 more source

Introducing Female Condoms to Female Sex Workers in Central America

International Perspectives on Sexual and Reproductive Health, 2010
Female condoms have a potential role in reducing HIV infection among female sex workers in Central America. Research on how to introduce female condoms to this population is warranted.Two rounds of focus groups with sex workers (115 in round one and 81 in round two) were conducted in El Salvador and Nicaragua in 2007-2008.
Natasha, Mack, Thomas G, Grey, Alexis, Amsterdam, Nancy, Williamson, Claudia Interiano, Matta   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Prevalence of Self-Reported Symptoms of Sexually Transmitted Infection among Establishment-Based Female Sex Workers in Ethiopia

Canadian Journal of Infectious Diseases and Medical Microbiology, 2020
Introduction. In spite of the fact that female sex workers being regarded as core transmitters of sexually transmitted infections to the general population, previous studies undertaken around STIs in Ethiopia fail to consider this segment of the ...
Shewangizaw Hailemariam, Aderajew Nigusse, Alemi Kebede   +2 more
doaj   +1 more source

Protection of female sex workers and social acceptance of female commercial sex workers in Indonesia

Simulacra
This article examines the social acceptance of female commercial sex workers in prostitution localities. Social acceptance is critical to their integration into the community. The research utilizes structuration theory to analyze the interplay between societal structures and individual agency in shaping community acceptance of these women.
Vivi Maulia Rahma, Fitriani Fazrin, Wahyu Pratama Tamba   +2 more
openaire   +1 more source

Female Sex Workers and Their Gatekeepers in China [PDF]

Qualitative Health Research, 2014
Female sex workers (FSWs) play a key role in HIV/AIDS transmission and their gatekeepers play a crucial role in shaping their behaviors. Limited studies are available on the relationship between FSWs and gatekeepers. In the current study we used an ethnographic approach to examine the dynamic and multidimensional relationship of FSWs and their ...
Yan, Hong, Chen, Zhang, Xiaoming, Li, Yuejiao, Zhou, Weigui, Guo   +4 more
openaire   +2 more sources