Results 241 to 250 of about 74,398 (287)
Advanced Science, EarlyView.Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai +12 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Female Sexual Dysfunction and Related Quality Of Life: Impact of Pelvic Floor Muscle Training
Eman Ali Abd El Moaty Sheha +3 more
openalex +1 more source
Managing female sexual dysfunction [PDF]
Urologic Oncology: Seminars and Original Investigations, 2022 Provide an overview of sexual dysfunction in female urologic cancer patients, approaches for assessing sexual problems, and interventions to treat sexual dysfunction in this patient population.A review of the literature in urologic oncology was conducted. Research on other female pelvic cancers with similar treatments was also reviewed.Sexual health is
Sarah S, Arthur +3 more
openaire +3 more sources
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Psychiatric Clinics of North America, 2009
Sexual dysfunctions diminish the quality of life for many women, frequently causing enough distress to warrant the diagnosis of a sexual disorder. Problems with sexual function can occur in any stage of the sexual response cycle. Dysfunction is further influenced by a variety of factors: medical, psychiatric, cultural, and stage of life.
Anita H, Clayton, David V, Hamilton
+8 more sources
Sexual dysfunctions diminish the quality of life for many women, frequently causing enough distress to warrant the diagnosis of a sexual disorder. Problems with sexual function can occur in any stage of the sexual response cycle. Dysfunction is further influenced by a variety of factors: medical, psychiatric, cultural, and stage of life.
Anita H, Clayton, David V, Hamilton
+8 more sources
BMJ, 2005
A common clinical problem In this issue (p 138), Ray Moynihan argues that female sexual dysfunction is essentially an invention of big pharmaceutical companies. He accuses Procter and Gamble of aggressively marketing awareness of a type of sexual dysfunction—female hypoactive desire disorder—to create a need for its new drug, transdermal testosterone
L, Zámecník, J, Dvorácek
+6 more sources
A common clinical problem In this issue (p 138), Ray Moynihan argues that female sexual dysfunction is essentially an invention of big pharmaceutical companies. He accuses Procter and Gamble of aggressively marketing awareness of a type of sexual dysfunction—female hypoactive desire disorder—to create a need for its new drug, transdermal testosterone
L, Zámecník, J, Dvorácek
+6 more sources
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2010
In recent years female sexual dysfunction (FSD) is increasingly being recognised. It has a detrimental effect on a woman's quality of life and includes a range of disorders, and therefore adequate screening and diagnosis of patients are necessary before appropriate treatment can be commenced.
Swati, Jha, Ranee, Thakar
openaire +4 more sources
In recent years female sexual dysfunction (FSD) is increasingly being recognised. It has a detrimental effect on a woman's quality of life and includes a range of disorders, and therefore adequate screening and diagnosis of patients are necessary before appropriate treatment can be commenced.
Swati, Jha, Ranee, Thakar
openaire +4 more sources
Medical Clinics of North America, 2017
Female sexual dysfunction can drastically diminish quality of life for many women. It is estimated that in the United States 40% of women have sexual complaints. These conditions are frequently underdiagnosed and undertreated. Terminology and classification systems of female sexual dysfunction can be confusing and complicated, which hampers the process
Anita H, Clayton +1 more
openaire +4 more sources
Female sexual dysfunction can drastically diminish quality of life for many women. It is estimated that in the United States 40% of women have sexual complaints. These conditions are frequently underdiagnosed and undertreated. Terminology and classification systems of female sexual dysfunction can be confusing and complicated, which hampers the process
Anita H, Clayton +1 more
openaire +4 more sources
The Obstetrician & Gynaecologist, 2021
Key content Female sexual dysfunction (FSD) is defined as any sexual complaint or problem resulting from disorders of desire, arousal, orgasm or sexual pain that causes marked distress or interpersonal difficulty. Various gynaecological problems such as pelvic organ prolapse and endometriosis affect sexual function and this impacts on their ...
Victoria Kershaw, Swati Jha
openaire +1 more source
Key content Female sexual dysfunction (FSD) is defined as any sexual complaint or problem resulting from disorders of desire, arousal, orgasm or sexual pain that causes marked distress or interpersonal difficulty. Various gynaecological problems such as pelvic organ prolapse and endometriosis affect sexual function and this impacts on their ...
Victoria Kershaw, Swati Jha
openaire +1 more source
Mayo Clinic Proceedings, 2002
Female sexual dysfunction (FSD) was recently recognized as arising from multiple organic etiologies; it is not primarily a psychological symptom as believed previously. A symptom-related complex resulting in physiologic changes, FSD can respond to either treatment of the underlying condition or supportive measures.
openaire +4 more sources
Female sexual dysfunction (FSD) was recently recognized as arising from multiple organic etiologies; it is not primarily a psychological symptom as believed previously. A symptom-related complex resulting in physiologic changes, FSD can respond to either treatment of the underlying condition or supportive measures.
openaire +4 more sources