Results 31 to 40 of about 77,069 (253)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Impact of Diabetes on Sexual Health regarding Female dysfunction Patients [PDF]

Port Said Scientific Journal of Nursing
Background Sexual dysfunction (SD) is one of the important problems in diabetes patients due to its complication effect on sexual function. The maternity nurse has an important role to assess the knowledge about needs for sexual health.
nermen atia, seham Ibrahim
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Disgust and Female Sexual Dysfunction

, 2023
Disgust is a natural disease-avoidance emotion experienced as an aversive feeling towards something subjectively offensive. In human sexuality, disgust plays an adaptive role, which consists of avoiding sexual behaviors that potentially lead to harm, such as transmission of diseases, unfavorable mate choices, or social exclusion.
Jan Wiecha, Magdalena Śmieja
openaire   +2 more sources

Rethinking Female Sexual Dysfunction: Shifting from Assumptions to Redefinition

Journal of Psychosexual Health
Objective: Female sexual dysfunction can be diagnosed when women report low sexual desire or arousal, orgasmic difficulties, or sexual pain, along with related distress.
Teagan Stotz, Robbie Eres
doaj   +1 more source

Predictors of female sexual dysfunction: a systematic review and qualitative analysis through gender inequality paradigms

BMC Women's Health, 2018
Background Female sexual dysfunction affects 41% of reproductive-age women worldwide, making it a highly prevalent medical issue. Predictors of female sexual dysfunction are multifaceted and vary from country to country.
Megan McCool-Myers, Melissa Theurich, Andrea Zuelke, Helge Knuettel, Christian Apfelbacher   +4 more
doaj   +1 more source

A Model for the Management of Female Sexual Dysfunctions [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2017
Introduction Sexual pleasure is fundamental for the maintenance of health and well-being, but it may be adversely affected by medical and psychosocial conditions. Many patients only feel that their health is fully restored after they resume normal sexual
Lúcia Alves da Silva Lara, Sandra Cristina Poerner Scalco, Júlia Kefalás Troncon, Gerson Pereira Lopes   +3 more
doaj   +1 more source