Results 111 to 120 of about 3,041,741 (386)

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

open access: yesAdvanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang   +4 more
wiley   +1 more source

Factors influencing physicians' advice about female sterilization in USA: a national survey.

open access: yesHuman Reproduction, 2011
BACKGROUND Tubal ligation can be a controversial method of birth control, depending on the patient's circumstances and the physician's beliefs. METHODS In a national survey of 1800 US obstetrician-gynecologist (Ob/Gyn) physicians, we examined how ...
R. Lawrence   +6 more
semanticscholar   +1 more source

ROS‐Activated Nanohydrogel Scaffolds with Multi‐Factors Controlled Release for Targeted Dual‐Lineage Repair of Osteochondral Defects

open access: yesAdvanced Science, EarlyView.
ROS‐activated nanohydrogels composite bilayer scaffolds are rationally designed for targted dual‐lineage repair of osteochondral defects. The as‐prepared nanohydrogel scaffolds provided 3D culture and induced dual‐lineage differentiation of BMSCs in vitro, efficiently inhibited early‐stage inflammation by rapidly releasing DS and improved cartilage and
Xiuhui Wang   +14 more
wiley   +1 more source

A Cross-Sectional Study to Understand Socio Demographic Profile of Couples Who Adopted Permanent Sterilization in Urban Slums of Surat City

open access: yesNational Journal of Community Medicine, 2013
Introduction: There is big gap in the adoption of male and female sterilization. It is necessary to understand socio demographic factors of couples who adopted permanent sterilization.
Ketan B Parmar   +4 more
doaj  

She Innovates- Female owner and firm innovation in India [PDF]

open access: yesarXiv, 2021
Using data from World Bank Enterprises Survey 2014, we find that having a female owner in India increases firm innovation probability using both input and output indicators of innovation. We account for possible endogeneity of female owner variable using a two stage instrumental variable probit model.
arxiv  

ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen   +10 more
wiley   +1 more source

A Facile Strategy to Restore the Optic Nerve Functionality Using an Injectable Conducting Hydrogel

open access: yesAdvanced Science, EarlyView.
An injectable conductive polymer hydrogel from poly (3,4‐ethylenedioxythiophene) (PEDOT) is developed to facilitate the recovery of electrophysiological function in injured optic nerve. The hydrogel can be injected directly at the injury site and spontaneously gel in place.
Changchun Yu   +12 more
wiley   +1 more source

Provision of female sterilization in Ribeirão Preto, São Paulo, Brazil

open access: yesCadernos de Saúde Pública, 2004
Forty percent of Brazilian married women from 15 to 49 years of age have undergone surgical sterilization. The 1988 Brazilian Constitution states that all scientifically proven contraceptive methods should be available to all citizens, but it was only in
Elisabeth Meloni Vieira   +1 more
doaj   +1 more source

Neutrino Oscillations With Two Sterile Neutrinos [PDF]

open access: yes, 2016
This work estimates the probability of $\mu$ to $e$ neutrino oscillation with two sterile neutrinos using a 5x5 U-matrix, an extension of the previous estimate with one sterile neutrino and a 4x4 U-matrix. The sterile neutrino-active neutrino mass differences and the mixing angles of the two sterile neutrinos with the three active neutrinos are taken ...
arxiv   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

open access: yesAdvanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang   +12 more
wiley   +1 more source

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