Results 121 to 130 of about 26,735 (288)

Safety outcomes of female sterilization by salpingectomy and tubal occlusion [PDF]

open access: gold, 2017
Julie Westberg   +2 more
openalex   +1 more source

Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Moderate exercise and low‐dose ellagic acid supplementation improved motor performance, learning, and longevity in a transgenic Drosophila model of Alzheimer's disease. Both interventions showed hormetic effects—that is, beneficial at low levels, but detrimental at higher intensities or doses.
Michelle Morgan   +2 more
wiley   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng   +10 more
wiley   +1 more source

(125) INVESTIGATING TRENDS IN MALE AND FEMALE STERILIZATION PROCEDURES AND FOLLOW-UP IN THE POST-DOBBS ERA [PDF]

open access: bronze
Joshua Schammel   +8 more
openalex   +1 more source

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding   +6 more
wiley   +1 more source

Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles   +6 more
wiley   +1 more source

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