Results 251 to 260 of about 3,621,977 (336)

A Cross-Sectional Assessment of Quality of Life Among Healthcare Professionals in North-Central Saudi Arabia: Implications for Workforce Well-Being and Policy Development. [PDF]

Healthcare (Basel)
Al-Hazmi AH, Alshammari FTM, Qazi I, ALruwaili BF, Abdel-Salam DM, Thirunavukkarasu A.   +5 more
europepmc   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Individual and institutional factors influencing dentists' practice in underserved areas. [PDF]

Sci Rep
Elani HW, Zhao N, Schuch HS, Saldutte G, Mertz E, Vujicic M.   +5 more
europepmc   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

LGBTIQA+ Inclusion in Aged Care: Perspectives From Providers and Community Stakeholders. [PDF]

Australas J Ageing
Tissot D, Karacsony S, Andrews S, James R.   +3 more
europepmc   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

Advancing Oral Health Workforce Equity in Gender and Sexual Orientation. [PDF]

Adv Dent Res
Ioannidou E, Araujo MWB, Bacino M, Randall C.   +3 more
europepmc   +1 more source

PEDOT:PSS—A Key Material for Bioelectronics

Advanced Science, EarlyView.
PEDOT:PSS ‐ Poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate ‐ is typically processed from water dispersions to form multifunctional and multidimensional constructs with tunable electronic and ionic conductivity. Throught processing engineering, PEDOT:PSS is intergrated in bioelectronic devices that operate efficiently in physiological conditions
Alan Eduardo Ávila Ramírez, David Pieter van der Laan, Mustafeez Bashir Shah, Liwen Wang, Erica Zeglio, Achilleas Savva   +5 more
wiley   +1 more source

Deriving Insights From an Occupational Incident Reporting System to Enhance Understanding of Musculoskeletal Incidents Among Nurses and Midwives. [PDF]

Nurs Open
Brusco N, Guerbaai RA, Graven C, Taylor NF, Hill K, Ekegren C, Haines T, Chu EMY, Kugler H, Rawson H, Abdelmotaleb R, Crabtree A, Dawes H, Collett J, Kandasamy D, Tan S, Dulfer F, Whittaker S, Collie A.   +18 more
europepmc   +1 more source