Results 181 to 190 of about 129,366 (266)

Clinical Characterization of Patients With 5q Spinal Muscular Atrophy Types 2 and 3 in Brazil: A Cross‐Sectional Observational Study

open access: yesClinical Genetics, EarlyView.
This study describes the clinical heterogeneity of Brazilian patients with 5q spinal muscular atrophy types 2 and 3, highlighting prolonged diagnostic delays and the impact of disease duration on motor function. Early genetic diagnosis and access to multidisciplinary care are crucial to preserve functional outcomes.
Elice Carneiro Batista   +31 more
wiley   +1 more source

Irradiated Liver Cancer Cell Vaccine Transfected With GM‐CSF Induces Specific and Long‐Lasting Anti‐tumour Immunity Through the Synergistic Effect of Oxidised mtDNA and GM‐CSF

open access: yesCell Proliferation, EarlyView.
Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song   +15 more
wiley   +1 more source

Maternal Hypoglycemia and Reduced Foetal Growth in Pregnancies Following Roux‐en‐Y Gastric Bypass: A Prospective Cohort Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction The risk of delivering a small‐for‐gestational‐age (SGA) neonate is increased after Roux‐en‐Y gastric bypass (RYGB). Because glucose is the foetus's primary energy source and postprandial hypoglycemia is common after RYGB, the Bariatric surgery And consequences for Mother and Baby In pregnancy (BAMBI) study examined associations ...
Louise L. Stentebjerg   +6 more
wiley   +1 more source

Coronary ostial plasty using femoral artery homograft following arterial switch operation. [PDF]

open access: yesJTCVS Tech
James L   +7 more
europepmc   +1 more source

Systematic screening for age‐related comorbidities: Health care optimization among persons with HIV in an outpatient setting

open access: yesHIV Medicine, EarlyView.
Abstract Background Age‐related comorbidities occur earlier and more frequently in people with HIV (PWH) than in the general population and have emerged as a key challenge in long‐term HIV care. Unfortunately, many of these conditions remain undiagnosed, and systematic screening in clinical practice remains limited.
Anna Katrine Haslund Roed   +4 more
wiley   +1 more source

Catheter Ablation: Evolution and Efficiencies

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

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