Results 271 to 280 of about 1,748,280 (337)

Standardization of In Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development

open access: yesArtificial Organs, EarlyView.
ABSTRACT Extracorporeal life support (ECLS) technology has witnessed remarkable advancements during the last decades. However, further research and development of devices are required to increase, for example, performance‐efficiency, hemocompatibility, and long‐term stability.
Jutta Arens   +41 more
wiley   +1 more source

Validation of Aortic Blood Flow Simulations During Extracorporeal Circulation Using Phase Contrast Magnetic Resonance Imaging

open access: yesArtificial Organs, EarlyView.
This is the first study assessing in vivo blood flow profiles during extracorporeal circulation (ECC) scenarios. Magnetic resonance imaging data served for the calibration of computational fluid dynamics algorithms, enabling accurate replication of the hemodynamic conditions.
Anna Kathrin Assmann   +9 more
wiley   +1 more source

Bilateral Supracondylar Process in a Subadult in the Late Antique Age: A Case Report

open access: yesArchaeometry, EarlyView.
ABSTRACT During the excavation procedures for the railway trait Napoli‐Cancello, in the city of Afragola (Naples), several burials dating back to the Late Antique Age were found. One of them was an amphora burial (enchytrismòs) and contained the skeletal remains of a subadult individual affected by bilateral supracondylar process. Supracondylar process
Barbara Albanese   +3 more
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja   +11 more
wiley   +1 more source

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