Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che +7 more
wiley +1 more source
Proximal femoral nail anti-rotation with and without cable cerclage for intertrochanteric femoral fractures with vulnerable lateral wall: a retrospective cohort study. [PDF]
Chen Y +5 more
europepmc +1 more source
ABSTRACT Freshwater turtles are valuable sentinels of aquatic systems due to their long lifespans and resilience in environments impacted by contaminants. The Permian Basin, dominated by the oil and gas sector, spans western Texas and southeastern New Mexico, USA, including the Pecos River and its tributaries, the Delaware and Black Rivers.
Ana G. G. Sapp +4 more
wiley +1 more source
Between-hospital variability in the management and outcomes of postoperative periprosthetic femoral fractures. [PDF]
Aryaie M +12 more
europepmc +1 more source
Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li +5 more
wiley +1 more source
Managing Vancouver B2 periprosthetic femoral fractures: is open reduction and internal fixation superior to stem revision? : A comparative analysis with a minimum 5-year follow-up. [PDF]
Wang T, Xu H, Wu J, Wang X.
europepmc +1 more source
Guidelines for Essential Trauma Care: Second Edition (2026)
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock +41 more
wiley +1 more source
Efficacy of Osteoporosis Treatment in Nonagenarians With Proximal Femoral Fractures: A Retrospective Cohort Study. [PDF]
Shitahodo T +8 more
europepmc +1 more source
Our understanding of the recolonization of northwest Europe in the period leading up to the Lateglacial Interstadial relies heavily on discoveries from Gough's Cave (Somerset, UK). Gough's Cave is the richest Late Upper Palaeolithic site in the British Isles, yielding an exceptional array of human remains, stone and organic artefacts, and butchered ...
Silvia M. Bello +2 more
wiley +1 more source
Risk Factors for Nonunion Following Lateral Locked Plating of Distal Femoral Fractures: A Bayesian Analysis of 560 Patients. [PDF]
Wagner RK +10 more
europepmc +1 more source

