Results 141 to 150 of about 106,955 (321)

Expert perspective: How, When, and Why to Potentially Stop Anti‐resorptive Drugs in Osteoporosis

open access: yesArthritis &Rheumatology, Accepted Article.
Osteoporosis is a chronic disease and anti‐resorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used anti‐resorptive treatments bisphosphonates and denosumab have short and longer term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G Saag
wiley   +1 more source

Age‐ and sex‐specific normative values of bone mineral density in the adult glenoid

open access: yesJournal of Orthopaedic Research, Volume 41, Issue 2, Page 263-270, February 2023., 2023
Abstract The objective of this study was to determine the normative bone mineral density (BMD) of cortical and trabecular bone regions in the adult glenoid and its dependence on the subject's age and sex. We analyzed computed tomography (CT) scans of 441 shoulders (310 males, 18–69 years) without any signs of glenohumeral joint pathology.
Pezhman Eghbali   +7 more
wiley   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

open access: yesMolecular Therapy: Nucleic Acids, 2019
Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral
Cheng Wang   +17 more
doaj  

Morphology of the dysplastic hip and the relationship with sex and acetabular version

open access: yesClinical Anatomy, EarlyView.
Abstract The dysplastic hip is characterized by incomplete coverage of the femoral head, resulting in increased risk of early osteoarthritis. The morphological variation of the hip joint is diverse and clear differences exist between females and males.
Inger Mechlenburg   +6 more
wiley   +1 more source

Effect of Sclerosis Bands in Femoral Head Necrosis on Non‐Vascularized Fibular Grafting—A Finite Element Study

open access: yesOrthopaedic Surgery
Objective Femoral head necrosis is a challenging condition in orthopaedics, and the occurrence of collapse is an important factor affecting the prognosis of femoral head necrosis.
Huang Yixuan   +8 more
doaj   +1 more source

Three‐dimensional assessment of subchondral arc and hip joint coverage angles in the asymptomatic young adult hip

open access: yesClinical Anatomy, EarlyView.
Abstract The primary objective of this study was to develop a custom algorithm to assess three‐dimensional (3D) acetabular coverage of the femoral head based on surface models generated from computed tomography (CT) imaging. The secondary objective was to apply this algorithm to asymptomatic young adult hip joints to assess the regional 3D acetabular ...
Holly D. Aitken   +6 more
wiley   +1 more source

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