Results 161 to 170 of about 1,930,858 (393)

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen   +13 more
wiley   +1 more source

Numerical investigation on the wear characteristics of hip implant under static loading

open access: yesHeliyon
Modern hip arthroplasty still faces the issue of wear in the articulating surface and wear induced debris. Thus, the design of hip implant is highly important for its longevity.
Jaber E. Abu Qudeiri   +3 more
doaj   +1 more source

An in vivo assay for osteoclast activity using mouse calvaria

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study describes a novel method for measuring osteoclast‐mediated bone resorption in vivo using a mouse model. Localized injection of RANKL in a basement membrane matrix above the cranium induced osteoclast‐mediated bone resorption. Utilizing micro‐computed tomography and a semiautomated three‐dimensional analysis program, osteoclast resorption pit
Christopher Grieg   +2 more
wiley   +1 more source

Renal vessel–assisted anastomosis improves the abdominal heart transplant model in rats without bilateral lower limb ischemia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A modified heterotopic heart transplantation (HTx) in rats was reported to improve the surgical success rate, in which the donor's vessels, the brachiocephalic trunk (BT) and the pulmonary artery (PA), were sutured to the recipient's left renal artery (RA) and left renal vein (RV).
Meng Wang, Wuxia Wang, Xunfeng Zou
wiley   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

open access: yesAnnals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek   +7 more
wiley   +1 more source

Expanding Indications of the Medial Femoral Condyle Free Flap: Systematic Review in Head and Neck Reconstruction

open access: gold, 2023
Niki K. Patel   +5 more
openalex   +1 more source

Generic, Geometric Finite Element Analysis of the Transtibial Residual Limb and Prosthetic Socket [PDF]

open access: yes, 1997
Finite element analysis was used to investigate the stress distribution between the residual limb and prosthetic socket of persons with transtibial amputation (TTA).
Childress, Dudley S.   +1 more
core   +1 more source

Silesaurid (Archosauria: Dinosauriformes) remains from the base of the Dockum Group (Late Triassic: Otischalkian) of Texas provide new insights to the North American record of dinosauriforms

open access: yesThe Anatomical Record, EarlyView.
Abstract Silesaurids (Archosauria: Dinosauriformes) are found in Middle to Upper Triassic deposits across Pangea, but few stratigraphic sections record the evolution of the group in one geographic area over millions of years. Here, we describe silesaurid remains from the oldest of the Upper Triassic stratigraphic sequence from the base of the Dockum ...
Frederick B. Tolchard   +2 more
wiley   +1 more source

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