Results 61 to 70 of about 186,455 (351)

Which Osteotomy for Osteonecrosis of the Femoral Head and Which Patient for the Osteotomy? [PDF]

, 2019
Transtrochanteric curved varus osteotomy (TCVO) and transtrochanteric rotational osteotomy (TRO) are joint-preserving procedures for osteonecrosis of the femoral head.
Ha, Yong-Chan, Koo, Kyung-Hoi, Lee, Beomseok, Lee, Young-Kyun, Parvizi, Javad   +4 more
core   +1 more source

Hard‐Magnetic Soft Millirobots in Underactuated Systems

Advanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang, Zixuan Zhang, Bingyan Li, Junkai Wang, Hongcheng Gu   +4 more
wiley   +1 more source

Femoral Head Reduction Osteotomy for the Treatment of Severe Femoral Head Deformities and Articular Incongruity in Children with Perthes Disease [PDF]

Travmatologiâ i Ortopediâ Rossii
Background. Lack of adequate treatment for children with Perthes disease leads to the formation of severe femoral head deformity with articular surfaces incongruity, followed by the development of femoroacetabular impingement and early hip osteoarthritis.
Pavel I. Bortulev, Tamila V. Baskaeva, Makhmud S. Poznovich, Dmitry B. Barsukov, Ivan Yu. Pozdnikin, Arslan N. Rustamov   +5 more
doaj   +1 more source

Viscoelastic properties of human and bovine articular cartilage : a comparison of frequency-dependent trends [PDF]

, 2016
Acknowledgments The authors would like to thank Spencer C. Barnes and Hamid Sadeghi for assistance during experimentation. We would also like to thank patients donating tissue and the surgeons collecting these.
Aspden, Richard M., Aspden, Richard M., Cederlund, Anna A., Espino, Daniel M., Lawless, Bernard M., Temple, Duncan K.   +5 more
core   +3 more sources

A Canine Musculoskeletal Robot for Investigating Biomechanical Functions During Locomotion

Advanced Robotics Research, EarlyView.
In this study, a dog limb musculoskeletal robot was developed using thin McKibben artificial muscles to investigate the effects of the dog's musculoskeletal structure on walking. Walking experiments were conducted in both indoor and outdoor environments, suggesting that the flexible structure of the dog's shoulders contributes to an increase in stroke ...
Hana Ito, Shoma Tanaka, Yunhao Feng, Hiroyuki Nabae, Yasuji Harada, Akira Fukuhara, Koichi Suzumori   +6 more
wiley   +1 more source

Proper mechanical stress promotes femoral head recovery from steroid-induced osteonecrosis in rats through the OPG/RANK/RANKL system

BMC Musculoskeletal Disorders, 2020
Background Long-term use of steroid may lead to osteonecrosis of the femoral head (ONFH). Mechanical stress may help bone formation and remodeling. This study aimed to probe the role of mechanical stress in the femoral head recovery in rats.
Dapeng Fu, Kairong Qin, Sheng Yang, Jianmin Lu, Haoyi Lian, Dewei Zhao   +5 more
doaj   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

A randomised controlled trial of total hip arthroplasty versus resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint [PDF]

, 2010
Background: Hip replacement (arthroplasty) surgery is a highly successful treatment for patients with severe symptomatic arthritis of the hip joint. For older patients, several designs of Total Hip Arthroplasty have shown excellent results in terms of ...
Achten, Juul, Costa, Matthew L., Edlin, Richard P., Griffin, Damian R., Parsons, Nicholas R.   +4 more
core   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

Molecular Therapy: Nucleic Acids, 2019
Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral
Cheng Wang, Weijia Sun, Shukuan Ling, Yu Wang, Xin Wang, Haoye Meng, Yuheng Li, Xueling Yuan, Jianwei Li, Ruoxi Liu, Dingsheng Zhao, Qiang Lu, Aiyuan Wang, Quanyi Guo, Shibi Lu, Hua Tian, Yingxian Li, Jiang Peng   +17 more
doaj   +1 more source