Results 81 to 90 of about 26,898 (195)

Experimental analysis of femoral head intraosseous vascular anastomosis in the treatment of porcine subcapital femoral neck fractures

Heliyon
Introduction: Femoral neck fractures are challenging injuries associated with a compromised blood supply to the femoral head, leading to a high risk of avascular necrosis and poor clinical outcomes. This study aimed to investigate the efficacy of femoral
Wei Deng, Jiaming Wan, Dingsong Wang, Kailong Geng, Guangliang Zhang, Ruixing Hou   +5 more
doaj   +1 more source

Frequency of Human Brucellosis Complications in West Asia: A Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
In 51.66% of the included studies in West Asia, the sample size was inadequate for at least half of the complications measured. ABSTRACT Background Brucellosis is a multi‐systemic zoonotic infection. The West Asia/Middle East region is an important global hotspot for brucellosis.
Aliasghar Fakhri‐Demeshghieh, Elnaz Rostamzaman, Fatemeh Sayareh, Amir Nikoukar, Faranak Farahani, Farniya Bakhtiary nia, Helia Sepahvand, Maryam Khaleghi, Mohammadsaeed Azamian, Mohammad Reza Shirzadi, Hesameddin Akbarein, Vahid Rahmanian   +11 more
wiley   +1 more source

Stem cell treatment for avascular necrosis of the femoral head: current perspectives

Stem Cells and Cloning: Advances and Applications, 2014
Matthew T Houdek,1 Cody C Wyles,2 John R Martin,1 Rafael J Sierra11Department of Orthopedic Surgery, 2School of Medicine, Mayo Clinic, Rochester, MN, USAAbstract: Avascular necrosis (AVN) of the femoral head is a progressive disease that predominantly ...
Houdek MT, Wyles CC, Martin JR, Sierra RJ   +3 more
doaj  

Three-dimensional distribution of subchondral fracture lines in osteonecrosis of the femoral head

Journal of Orthopaedic Translation
Objective: To investigate the characteristics of three-dimensional distribution of subchondral fracture lines on the surface of the osteonecrosis femoral head, and to discuss the underlying mechanisms that contribute to its collapse.
Yan-Bin Wu, Guang-Bo Liu, Huo Li, Jia-Zhou Wu, Jin-Shu Tang, Jian-Ting Ye, Ying-Jie Xiong, Xi-Wei Peng, Ze-Xian Liu, Yu-Zheng Lu, Cong-Cong Guan, Hao-Ye Meng, Xiao-Han Sun, Xin Wang, Ai-Yuan Wang, Zhe Zhao, Yuan Hu, Yu-Feng Liu, Li-Jun Sun, Ling Qin, Jiang Peng   +20 more
doaj   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Post radiotherapy femoral head avascular necrosis

Radiology Case Reports
Osteonecrosis is the death of bone cells due to insufficient blood supply; radiotherapy for various underlying malignancies is one of the uncommon causes. Microvascular damage or underlying tissue fibrosis, which leads to an ischemic environment and cell
Amanuel A. Ketema, MD, Bemnet T. Gebregiorigis, Michael T. Abera, MD, Lidet G. Amha, MD, Sonia W. Semayneh, MD   +4 more
doaj   +1 more source

Integrated Multi‐Time‐Point 18F‐FAPI PET/CT and Immune Histopathology for Predicting Pathological Complete Response in Microsatellite‐Stable Locally Advanced Rectal Cancer Treated With Neoadjuvant Radiotherapy, Chemotherapy, and Immunotherapy

MedComm, Volume 7, Issue 10, October 2026.
Serial multi‐time‐point 18F‐FAPI PET/CT‐derived stromal kinetics and baseline immune‐histopathological features, including iTLS count and B‐cell density, jointly predicted pCR in MSS locally advanced rectal cancer. The resulting four‐variable model achieved a mean nested cross‐validated AUC of 0.874.
Minyi He, Huiting Yang, Yunxing Shi, Rongqin Zhang, Taixuan Wan, Xiaolin Pang, Zhanwen Zhang, Liang Huang   +7 more
wiley   +1 more source

Small Proteoglycans, Big Impact: Decorin, Biglycan, and Asporin in Musculoskeletal Tissue Health and Disease

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT The extracellular matrix (ECM) is a dynamic and information‐rich network that integrates structural support with biochemical and mechanical signaling. Among its key regulatory components are the Small Leucine‐Rich Proteoglycans (SLRPs), a family of matrix molecules that coordinate extracellular architecture with cell signaling.
Alessandra Leone, Zsuzsa Jenei‐Lanzl, Frank Zaucke   +2 more
wiley   +1 more source

Fat‐Containing Soft Tissue Lesions of the Limbs and Body Wall—A Pictorial Essay

Journal of Medical Imaging and Radiation Oncology, Volume 70, Issue 7, Page 657-666, October 2026.
ABSTRACT Lipomatous tumours are frequently encountered on imaging. The spectrum of lipomatous tumours ranges from simple lipomas, which can be monitored clinically, to high‐grade liposarcomas, which require timely, multidisciplinary management. The presence of fat within lesions may also be observed in non‐lipomatous tumours, as well as in a variety of
Kai‐Zheong Lim, Cathryn Hui
wiley   +1 more source

uPAR‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor

Aging Cell, Volume 25, Issue 10, October 2026.
GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng, Xiaozhu Zeng, Jing Guo, Lihong Li, Shirui Zou, Nan Liu, Shuai He, Lanzhen Yan, Qiong Wang, Yongjie Zhu, Ben Wang, Dong Yang, Longbao Lv, Xudong Zhao   +13 more
wiley   +1 more source