Results 101 to 110 of about 152,173 (338)

Dual‐Modular Hydrogel Microparticles with Precision‐Modulation of Inflammatory Microenvironment Dictate Full‐Thickness Cartilage Regeneration for Osteoarthritis Repair

open access: yesAdvanced Science, EarlyView.
Cartilage injury is a prominent pathological hallmark of osteoarthritis. In this study, we developed a two‐modular hydrogel microparticle system wherein HMP‐A effectively targets the damaged area, while HMP‐B forms an efficient connection with HMP‐A on the cartilage surface.
Xinye Chen   +5 more
wiley   +1 more source

Treatment of Femoral Neck Fractures with Intramedullary Fixation with Integrated Interlocking Lag and Compression Screws

open access: yesJournal of Limb Lengthening & Reconstruction
Objectives: (1) To describe our operative technique for femoral neck fractures using an intramedullary device with integrated compression screws. (2) Retrospective analysis of patients treated with intramedullary fixation with interlocking lag and ...
Bradley Lezak   +2 more
doaj   +1 more source

Development of a test system to analyze different hip fracture osteosyntheses under simulated walking [PDF]

open access: yes, 2012
The mechanical complications of osteosyntheses after hip fractures are previously investigated by mostly static or dynamic uniaxial loading test systems.
Bachmeier, Samuel   +5 more
core   +1 more source

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong   +15 more
wiley   +1 more source

Intraoperative angulation of the C-arm for X-ray of each curved surface of the femoral neck wall: a cadaveric study

open access: yesBMC Musculoskeletal Disorders
Background C-arm fluoroscopy is the main method assisting surgical reduction and internal fixation of the femoral neck, as traditional anteroposterior and lateral fluoroscopy is insufficient for visualizing the irregular anatomical structure of the ...
Qiu-liang Zhu   +5 more
doaj   +1 more source

Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis

open access: yesAdvanced Science, EarlyView.
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart   +4 more
wiley   +1 more source

The Effect of Immersion Technology on the Quality of Life in Older Adults: A Systematic Review

open access: yesAGING MEDICINE, EarlyView.
Immersive technologies, especially virtual reality (VR), significantly improve the quality of life for older adults by enhancing physical health, cognitive function, and psychological well‐being. These technologies can be adapted to meet individual needs, making them an effective tool for addressing the challenges of aging.
Solmaz Sohrabei   +2 more
wiley   +1 more source

Clinical application of the Femoral Neck System in femoral neck fractures

open access: yesAsian Journal of Surgery, 2023
Hao Zeng   +3 more
openaire   +3 more sources

Immunostimulatory DNA Tetrahedron‐Based Nanovaccine Combined With Immune Checkpoint PD‐1 Blockade for Boosting Systemic Immune Responses Against Oral Squamous Cell Carcinoma

open access: yesAggregate, EarlyView.
This study introduces an immunomodulatory DNA tetrahedral framework nucleic acid‐based nanovaccine tFNA‐CpG. The functionalized nanovaccine shows stable and well‐defined morphological characteristics and can be efficiently taken up by APCs. When combined with the immune checkpoint inhibitor anti‐PD‐1, it notably ameliorated the immunosuppressive ...
Xueting Yang   +12 more
wiley   +1 more source

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