Results 101 to 110 of about 842,977 (363)

The Cerebrospinal Fluid Secretion Rate Increases in Awake and Freely Moving Rats but Differs With Experimental Methodology

Advanced Science, EarlyView.
CSF dynamics are vital for neurological health. Yet accurate quantification of CSF rates is challenging. Using a novel technique in awake, freely moving rats, significantly higher secretion rates are found than in anesthetized rats. The findings highlight the importance of awake models and the adaptability of methods for studying CSF changes influenced
Trine L. Toft‐Bertelsen, Beatriche L. Edelbo, Annette B. Steffensen, Sara D. Lolansen, Jonathan H. Wardman, Dennis B. Jensen, Nanna MacAulay   +6 more
wiley   +1 more source

Automatic Hip Fracture Identification and Functional Subclassification with Deep Learning [PDF]

arXiv, 2019
Purpose: Hip fractures are a common cause of morbidity and mortality. Automatic identification and classification of hip fractures using deep learning may improve outcomes by reducing diagnostic errors and decreasing time to operation. Methods: Hip and pelvic radiographs from 1118 studies were reviewed and 3034 hips were labeled via bounding boxes and ...
arxiv  

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

Advanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao, Qirong Xie, Qiang Zheng, Jingping Zhang, Mengyu Yao, Zhongyong Du, Lujun Zhang, Tianyang Hu, Yunli Zhao, Jianlin Du, Yongyong Li, Yuxing Feng, ND Melgiri, Xiaodong Zhao, Rongzhong Huang, Yang Sun   +15 more
wiley   +1 more source

Correcting rotational error in rectal cancer radiation therapy: Can planning target volume margins be safely reduced?

Journal of Medical Radiation Sciences, Volume 69, Issue 4, Page 473-483, December 2022., 2022
To evaluate the magnitude and resulting impact of rotational error in rectal cancer patients, and to investigate the feasibility of planning target volume (PTV) margin reduction to improve organs‐at‐risk (OAR) sparing. Abstract Introduction The magnitude and impact of rotational error is unclear in rectal cancer radiation therapy.
Vivian Seah, Kylie Dundas, Felicity Hudson, Yolanda Surjan, Rebecca Bartlett, Rebecca Ko, Sandie Smith, Sankar Arumugam, Meredith Johnston, Karen Wong, Mark Lee   +10 more
wiley   +1 more source

The prevalence of fracture extension in displaced femoral neck fractures in the elderly

OTA International, 2019
. Objective:. Arthroplasty is the common treatment for intracapsular femoral neck fractures in the elderly. Recent studies have shown that there may be more overall complications related to uncemented hemiarthroplasty compared to cemented, including more
Kyle Matsuo Natsuhara, MD, Robert Downey Boutin, MD, Mark Andrew Lee, MD, John Patrick Meehan, MD   +3 more
doaj   +1 more source

Predictive Analysis for Detection of Human Neck Postures using a robust integration of kinetics and kinematics [PDF]

arXiv, 2020
Human neck postures and movements need to be monitored, measured, quantified and analyzed, as a preventive measure in healthcare applications. Improper neck postures are an increasing source of neck musculoskeletal disorders, requiring therapy and rehabilitation.
arxiv  

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

Advanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan, Renwang Sheng, Weikun Li, Yinghua Tao, Zonghao Liu, Ning Yang, Syeda Safia Hashmi, Feiling Feng, Fangzhou Liu, Liqin Ge   +9 more
wiley   +1 more source

Acute toxicity and patient‐reported outcomes in anal canal cancer: results of a pilot study

Journal of Medical Radiation Sciences, Volume 69, Issue 4, Page 484-491, December 2022., 2022
After reaching their maximum at the end of treatment, the majority of toxicity and patient reported outcomes (PROs) items approached baseline levels by 3 months post treatment. The results of this study suggest that PROs are an important complementary tool to Common Terminology Criteria for Adverse Effects (CTCAE) and provide greater understanding of ...
Elizabeth Brown, Emma Le Cornu, Thanh Bui, Anne Bernard, Tao Mai, Jennifer Harvey   +5 more
wiley   +1 more source

Should Nonunion Femoral Neck Fractures in Children be Treated with Extracorporeal Shockwave Therapy Under Navigation Guidance?

Interdisciplinary Neurosurgery, 2020
Purpose: To present the accuracy and safety of treat nonunion of children femoral neck fracture using the technique with extracorporeal shockwave therapy (ESWT) under navigation guidance.
Wei He, Anyi Guo, Shan Wang, Longhao Zhang, Yajun Liu   +4 more
doaj  

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source