Results 71 to 80 of about 842,977 (363)

The role of microscopic properties on cortical bone strength of femoral neck

BMC Musculoskeletal Disorders, 2023
Background Femoral neck fractures are serious consequence of osteoporosis (OP), numbers of people are working on the micro—mechanisms of femoral neck fractures.
Ning Xia, Yun Cai, Qianhua Kan, Jian Xiao, Lin Cui, Jiangjun Zhou, Wei Xu, Da Liu   +7 more
doaj   +1 more source

Fully Automated Organ Segmentation in Male Pelvic CT Images [PDF]

Balagopal A, Kazemifar S, Nguyen D, Lin M H, Hannan R, Owrangi A and Jiang S 2018 Fully automated organ segmentation in male pelvic CT images Phys. Med. Biol. 63 245015, 2018
Accurate segmentation of prostate and surrounding organs at risk is important for prostate cancer radiotherapy treatment planning. We present a fully automated workflow for male pelvic CT image segmentation using deep learning. The architecture consists of a 2D localization network followed by a 3D segmentation network for volumetric segmentation of ...
arxiv   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source

Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 186-197, January 2023., 2023
ABSTRACT Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ERα (Ot‐ERα) regulated trabecular, but not ...
Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxim A. Gallant, Claes Ohlsson, Teresita M. Bellido, Russell P. Main   +6 more
wiley   +1 more source

New technology: clinical efficacy of intracapsular decompression and supported hollow screw treatment for Garden IV femoral neck fractures

European Journal of Medical Research
Background The management of Garden IV femoral neck fractures presents a formidable challenge. This study aimed to assess the safety and efficacy of a novel technological approach for treating Garden IV femoral neck fractures, involving intracapsular ...
Zhaofeng Jia, Tinghui Xiao, Yimiao Lin, Wenjun Huang, Peizhi Deng, Jiandong Lin, Shiyuan Lin, Jiwu Cheng, Fengting Cui, Xinjia Hu, Xiaoming Zhang   +10 more
doaj   +1 more source

Osteonecrosis of femoral head in young patients with femoral neck fracture: a retrospective study of 250 patients followed for average of 7.5 years

Journal of Orthopaedic Surgery and Research, 2020
Objective To investigate the risk factors for osteonecrosis of the femoral head (ONFH) after the treatment of femoral neck fracture in patients under 60 years old.
Fang Pei, Rui Zhao, Fenglei Li, Xiangyang Chen, KaiJin Guo, Liang Zhu   +5 more
doaj   +1 more source

Universal Hydrogel Carrier Enhances Bone Graft Success: Preclinical and Clinical Evaluation

Advanced Healthcare Materials, EarlyView.
TX hydrogel improves the delivery of different types of particulate bone grafts, maintaining them at the implantation sites, and resulting in favorable bone regenerative outcomes. Abstract Orthopedic, maxillofacial, and complex dentoalveolar bone grafting procedures that require donor‐site bone harvesting can be associated with post‐surgical ...
Dax Calder, Farshad Oveissi, Simin Maleknia, Tom Huang, Bernard Koong, Terence Abrams, Andrew Oar, Wojciech Chrzanowski, Fariba Dehghani, Ali Fathi   +9 more
wiley   +1 more source

Reduced Bone Mass and Increased Osteocyte Tartrate‐Resistant Acid Phosphatase (TRAP) Activity, But Not Low Mineralized Matrix Around Osteocyte Lacunae, Are Restored After Recovery From Exogenous Hyperthyroidism in Male Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 131-143, January 2023., 2023
ABSTRACT Hyperthyroidism causes secondary osteoporosis through favoring bone resorption over bone formation, leading to bone loss with elevated bone fragility. Osteocytes that reside within lacunae inside the mineralized bone matrix orchestrate the process of bone remodeling and can themselves actively resorb bone upon certain stimuli.
Eva Maria Wölfel, Franziska Lademann, Haniyeh Hemmatian, Stéphane Blouin, Phaedra Messmer, Lorenz C. Hofbauer, Björn Busse, Martina Rauner, Katharina Jähn‐Rickert, Elena Tsourdi   +9 more
wiley   +1 more source

A Computer-Aided Diagnosis System Using Artificial Intelligence for Hip Fractures -Multi-Institutional Joint Development Research- [PDF]

arXiv, 2020
[Objective] To develop a Computer-aided diagnosis (CAD) system for plane frontal hip X-rays with a deep learning model trained on a large dataset collected at multiple centers. [Materials and Methods]. We included 5295 cases with neck fracture or trochanteric fracture who were diagnosed and treated by orthopedic surgeons using plane X-rays or computed ...
arxiv  

Infant hip screening using multi-class ultrasound scan segmentation [PDF]

arXiv, 2022
Developmental dysplasia of the hip (DDH) is a condition in infants where the femoral head is incorrectly located in the hip joint. We propose a deep learning algorithm for segmenting key structures within ultrasound images, employing this to calculate Femoral Head Coverage (FHC) and provide a screening diagnosis for DDH.
arxiv