Results 11 to 20 of about 51,438 (334)

Risk of osteoporosis in testicular germ cell tumour survivors: A systematic review of the literature

BJUI Compass, Volume 4, Issue 1, Page 24-43, January 2023., 2023
Abstract Context Testicular germ cell tumour (TGCT) survivors are potentially at risk of developing osteoporosis, because of increased risk for disturbed bone remodelling associated with hypogonadism and anti‐cancer treatment. A number of studies show bone loss and increased fracture risk in TGCT survivors, but data are scarce.
Josephina P. M. Vrouwe, Pauline M. L. Hennus, Neveen A. T. Hamdy, Susanne Osanto, Peter‐Paul M. Willemse   +4 more
wiley   +1 more source

ENPP1 deficiency: A clinical update on the relevance of individual variants using a locus‐specific patient database

Human Mutation, Volume 43, Issue 12, Page 1673-1705, December 2022., 2022
Abstract Loss‐of‐function variants in the ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) cause ENPP1 Deficiency, a rare disorder characterized by pathological calcification, neointimal proliferation, and impaired bone mineralization. The consequence of ENPP1 Deficiency is a broad range of age dependent symptoms and morbidities
Stephanie A. Mercurio, Lauren M. Chunn, Gus Khursigara, Catherine Nester, Kathleen Wray, Ulrike Botschen, Mark J. Kiel, Frank Rutsch, Carlos R. Ferreira   +8 more
wiley   +1 more source

Longitudinal Change in Bone Density, Geometry, and Estimated Bone Strength in Older Men and Women From The Gambia: Findings From the Gambian Bone and Muscle Aging Study (GamBAS)

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 48-58, January 2023., 2023
ABSTRACT Musculoskeletal aging in the most resource‐limited countries has not been quantified, and longitudinal data are urgently needed to inform policy. The aim of this prospective study was to describe musculoskeletal aging in Gambian adults. A total of 488 participants were recruited stratified by sex and 5‐year age band (aged 40 years and older ...
Mícheál Ó Breasail, Camille Pearse, Ayse Zengin, Landing Jarjou, Cyrus Cooper, Peter R Ebeling, Ann Prentice, Kate A Ward   +7 more
wiley   +1 more source

Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 186-197, January 2023., 2023
ABSTRACT Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ERα (Ot‐ERα) regulated trabecular, but not ...
Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxim A. Gallant, Claes Ohlsson, Teresita M. Bellido, Russell P. Main   +6 more
wiley   +1 more source

Reduced Bone Mass and Increased Osteocyte Tartrate‐Resistant Acid Phosphatase (TRAP) Activity, But Not Low Mineralized Matrix Around Osteocyte Lacunae, Are Restored After Recovery From Exogenous Hyperthyroidism in Male Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 131-143, January 2023., 2023
ABSTRACT Hyperthyroidism causes secondary osteoporosis through favoring bone resorption over bone formation, leading to bone loss with elevated bone fragility. Osteocytes that reside within lacunae inside the mineralized bone matrix orchestrate the process of bone remodeling and can themselves actively resorb bone upon certain stimuli.
Eva Maria Wölfel, Franziska Lademann, Haniyeh Hemmatian, Stéphane Blouin, Phaedra Messmer, Lorenz C. Hofbauer, Björn Busse, Martina Rauner, Katharina Jähn‐Rickert, Elena Tsourdi   +9 more
wiley   +1 more source

Lipopolysaccharide‐Induced Bone Loss in Rodent Models: A Systematic Review and Meta‐Analysis

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 198-213, January 2023., 2023
ABSTRACT Osteoporosis has traditionally been characterized by underlying endocrine mechanisms, though evidence indicates a role of inflammation in its pathophysiology. Lipopolysaccharide (LPS), a component of gram‐negative bacteria that reside in the intestines, can be released into circulation and stimulate the immune system, upregulating bone ...
Kirsten N. Bott, Evelyn Feldman, Russell J. de Souza, Elena M. Comelli, Panagiota Klentrou, Sandra J. Peters, Wendy E. Ward   +6 more
wiley   +1 more source

Age‐ and sex‐specific normative values of bone mineral density in the adult glenoid

Journal of Orthopaedic Research, Volume 41, Issue 2, Page 263-270, February 2023., 2023
Abstract The objective of this study was to determine the normative bone mineral density (BMD) of cortical and trabecular bone regions in the adult glenoid and its dependence on the subject's age and sex. We analyzed computed tomography (CT) scans of 441 shoulders (310 males, 18–69 years) without any signs of glenohumeral joint pathology.
Pezhman Eghbali, Fabio Becce, Patrick Goetti, Frederic Vauclair, Alain Farron, Philippe Büchler, Dominique Pioletti, Alexandre Terrier   +7 more
wiley   +1 more source

Challenging the dogma to “always operate” acute hip fractures: a proof-of-concept pilot study for nonoperative management of undisplaced femoral neck fractures

Patient Safety in Surgery, 2022
Background The notion that all acute hip fractures are a surgical entity requiring either surgical fracture fixation or hip replacement represents a historic dogma, particularly within the orthopaedic community of the United States.
Juan Manuel Vinas-Rios, Jan-Henning Wölm, Richard Martin Sellei, Andreas Ladenburger   +3 more
doaj   +1 more source

Femoral Neck Angle Impacts Hip Disorder and Surgical Intervention: A Patient-Specific 3D Printed Analysis [PDF]

ACM International Conference Proceeding Series 2019, 2020
The purpose of this study is to investigate the femoral neck angulation for prediction of the complication associated with dynamic hip screw (DHS) surgery and hip deformity. Three sample patients' MRI images were selected to calculate the femoral neck angles.
arxiv   +1 more source

Treatment of postoperative non-union with internal fixation loosening of Garden IV femoral neck fracture with teriparatide in a young adult: A case report

Frontiers in Surgery, 2022
BackgroundPostoperative non-union of femoral neck fracture often needs secondary operation. We report a case of a postoperative non-union of femoral neck fracture treated with teriparatide.Case presentationA young male patient with Garden IV femoral neck
Lili Lai, Yifan Li, Miaoda Shen, Xuanwei Wang, Cheng Zhong, Sanzhong Xu   +5 more
doaj   +1 more source