Results 61 to 70 of about 180,308 (392)

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Early postoperative delirium after hemiarthroplasty in elderly patients aged over 70 years with displaced femoral neck fracture

Clinical Interventions in Aging, 2017
Purpose Postoperative delirium is a risk factor for worse outcome after hip fracture surgery in elderly patients. Postoperative delirium is associated with anesthesia, postoperative pain, and patient factors.
Y. Choi, Dae-Hwan Kim, Tae-Young Kim, Taewan Lim, S. Kim, Jehyun Yoo   +5 more
semanticscholar   +1 more source

Dual‐Biomimetic Bone Adhesive with Osteoimmunomodulatory Capabilities for Anatomical Reconstruction of Comminuted Fractures

Advanced Science, EarlyView.
A structurally and functionally dual bionic bone adhesive is engineered through an organic–inorganic cohesion strategy, which significantly reinforces the adhesive's bone tissue adhesion as well as osteogenic activity. In a pioneering rabbit radius comminuted fracture model, the bone adhesive exhibits exceptional capability in immobilizing bone ...
Junyao Cheng, Hufei Wang, Ming Li, Jianpeng Gao, Xiao Liu, Chuyue Zhang, Pengfei Chi, Bo Li, Yuan Xve, Daoyang Fan, Zheng Wang, Jianheng Liu, Xing Wang, Licheng Zhang   +13 more
wiley   +1 more source

Morfología femoral proximal en fracturas de cadera [PDF]

, 2003
Es frecuente observar como pacientes que han sufrido una fractura de cadera, si se fracturan posteriormente la cadera contralateral, es del mismo tipo que la primera fractura.
Albareda Albareda, Jorge Cruz, Calvo de Mora Rebollo, María Jesús, Lasierra Sanromán, José Manuel, Martín Ruiz, G., Seral García, Belén, Seral Iñigo, Fernando   +5 more
core  

Management and radiographic outcomes of femoral head fractures. [PDF]

, 2017
BackgroundFemoral head fractures are uncommon injuries. Small series constitute the majority of the available literature. Surgical approach and fracture management is variable. The purpose of this study was to evaluate the incidence, method of treatment,
Firoozabadi, Reza, Krieg, James C, Marecek, Geoffrey, Routt, Milton Lee Chip, Scolaro, John A   +4 more
core   +3 more sources

Femoral neck fracture osteosynthesis by the biplane double-supported screw fixation method (BDSF) reduces the risk of fixation failure: clinical outcomes in 207 patients

Archives of Orthopaedic and Trauma Surgery, 2017
IntroductionOsteosynthesis of femoral neck fractures is related up to 46% rate of complications. The novel method of biplane double-supported screw fixation (BDSF; Filipov’s method) offers better stability using three medially diverging cannulated screws
Orlin Filipov, K. Stoffel, B. Gueorguiev, C. Sommer   +3 more
semanticscholar   +1 more source

Femoral Neck Fracture [PDF]

Hip & Pelvis, 2010
The incidence of the femoral neck fracture is increasing, and the mechanism of the injuries is quite different in the young and elderly groups (high energy injury and osteoporosis, respectively). In the young group, early anatomical reduction and rigid fixation by such measures as multiple cannulated screws are mandatory to decrease the complications ...
Jin Myong Dan, Hyung Ku Yoon
openaire   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Fractura por estrés del cuello femoral sobre clavo centromedular en cerrojo [PDF]

, 1994
Se presenta un caso de fractura de estrés del cuello femoral en una paciente de 81 años de edad, a los 7 meses del tratamiento de una fractura de diáfisis femoral mediante clavo intramedular en cerrojo estático.
Albareda Albareda, Jorge Cruz, Palanca Martín, Daniel, Segura Mata, J., Seral Iñigo, Fernando   +3 more
core  

Successful treatment for bilateral femoral neck insufficiency fractures: a rare lesion case report and an updated review of the literature

BMC Musculoskeletal Disorders, 2020
Background The incidence of insufficiency fracture (IF) at femoral neck is low, accounting for about 5% of all insufficiency fractures, and IF at bilateral femoral neck is less common with more occurrence in athlete or serviceman.
Xu-yi Tan, Ting Lei, Guan-bao Wu, Hai-en Luo, Gang Huang, Can-yu He, Min Lu, Peng-fei Lei   +7 more
doaj   +1 more source