Results 191 to 200 of about 76,338 (329)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Design of a porous biodegradable internal fixation for the treatment of pauwels type III femoral neck fractures. [PDF]

open access: yesFront Bioeng Biotechnol
Liu C   +10 more
europepmc   +1 more source

Osteoblastic metastasis secondary to mammary carcinoma in a dog (Canis lupus familiaris) presenting with lameness

open access: yesVeterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract Osteoblastic metastases occur secondary to malignant epithelial tumours, and lead to marked periosteal hyperostosis and medullary sclerosis. These are rarely reported in dogs. A 7‐year‐old, neutered, female labrador retriever × standard poodle presented with a 4‐week history of progressive right hindlimb lameness, pyrexia and thoracolumbar ...
David Sheehan   +5 more
wiley   +1 more source

Survival Outcomes in Breast Cancer Patients With Metastatic Bone Disease

open access: yesWorld Journal of Surgery, Volume 49, Issue 12, Page 3326-3334, December 2025.
To evaluate the survival outcomes of breast cancer patients with metastatic bone disease and to assess whether these patients exhibit different prognoses compared to those with more extensive metastatic involvement. ABSTRACT Objective To evaluate the survival outcomes of breast cancer patients with metastatic bone disease and to assess whether these ...
Gerard J. Hill   +11 more
wiley   +1 more source

Bipolar hemiarthroplasty for femoral neck fractures in elderly patients: a retrospective study of 1001 patients. [PDF]

open access: yesArch Orthop Trauma Surg
Gerber F   +4 more
europepmc   +1 more source

Urinary retention as a postoperative complication associated with functional decline in elderly female patients with femoral neck and trochanteric fractures

open access: gold, 2019
Toshihiro Higashikawa   +13 more
openalex   +1 more source

Association Between Arterial Stiffness and Bone Microarchitectural Deterioration in Type 2 Diabetes: A Cross‐Sectional Study

open access: yesJournal of Diabetes, Volume 17, Issue 12, December 2025.
Identified baPWV as a novel independent influencing factor of bone microarchitecture deterioration in T2DM, elucidating a bone–vascular axis. Proposes baPWV as a practical indicator for simultaneous cardiovascular and fracture risk assessment in diabetic patients.
Yangting Wang   +5 more
wiley   +1 more source

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