Results 41 to 50 of about 66,363 (264)

The rendezvous technique for the treatment of ipsilateral femoral neck and shaft fractures: A case series

Trauma Case Reports, 2020
Concomitant ipsilateral femoral neck and shaft fractures are uncommon high-energy injuries characteristically occurring in young adults. Between 75 and 100% of these injuries occur in association with polytrauma to other organ systems. Associated femoral
Seun Harewood, Marlon M. Mencia, Patrick Harnarayan   +2 more
doaj   +1 more source

Performance of the resurfaced hip. Part 1: the influence of the prosthesis size and positioning on the remodelling and fracture of the femoral neck

, 2010
Hip resurfacing is an established treatment for osteoarthritis in young active patients. Failure modes include femoral neck fracture and prosthesis loosening, which may be associated with medium-term bone adaptation, including femoral neck narrowing and ...
Browne, Martin, Dickinson, Alexander, Taylor, Andrew C.   +2 more
core   +1 more source

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]

, 2006
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra, Anne-Margriet Huisman, Ans C.M. Oostveen, Ben A.C. Dijkmans, Chris E.D. de Laet, de Nijs RN, Erik Buskens, George A.W. Bruyn, Johannes W.G. Jacobs, Johannes W.J. Bijlsma, Michel BA, Piet P.M.M. Geusens, Roland F.J. Laan, Ron N.J. de Nijs, Willem F. Lems   +14 more
core   +4 more sources

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Bio-mechanical effects of femoral neck system versus cannulated screws on treating young patients with Pauwels type III femoral neck fractures: a finite element analysis

BMC Musculoskeletal Disorders
Introduction As a novel internal fixation for femoral neck fractures, the femoral neck system has some advantages for young Pauwels type III femoral neck fractures without clear biomechanical effects and mechanisms. Thus, the objection of the study is to
Xiao Fan, Yimin Zhou, Shiyou Dai, Kecheng Lao, Qiliang Zhang, Tengbo Yu   +5 more
doaj   +1 more source

Bone mineral density and risk of heart failure in older adults: The Cardiovascular Health Study [PDF]

, 2017
Background Despite increasing evidence of a common link between bone and heart health, the relationship between bone mineral density ( BMD ) and heart failure ( HF
Bartz, Traci M, Brown, David L, Carbone, Laura D, Chaves, Paulo H.M., Civitelli, Roberto, Fohtung, Raymond B, Kestenbaum, Bryan R, Kizer, Jorge R, Koh, William J.H., Stein, Phyllis K   +9 more
core   +2 more sources

Ability of fitness testing to predict injury risk during initial tactical training: a systematic review and meta-analysis [PDF]

, 2020
OBJECTIVE: Tactical personnel (Military, Law Enforcement, Emergency Responders) require physical fitness levels sufficient for training and occupational duty.
Orr, Robin, Sawyer, Sally, Schram, Ben, Tomes, Colin D   +3 more
core   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

A non-synonymous coding change in the CYP19A1 gene Arg264Cys (rs700519) does not affect circulating estradiol, bone structure or fracture [PDF]

, 2011
Background The biosynthesis of estrogens from androgens is catalyzed by aromatase P450 enzyme, coded by the CYP19A1 gene on chromosome 15q21.2. Genetic variation within the CYP19A1 gene sequence has been shown to alter the function of the enzyme.
Wang, J.Z., Deogan, M.S., Lewis, J.R., Chew, S., Mullin, B.H., McNab, T.J., Wilson, S.G., Ingley, E., Prince, R.L.   +8 more
core   +3 more sources

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source