Results 111 to 120 of about 515,490 (195)

Bone Marrow Mesenchymal Stem Cells Rescue Tendon Injury by Regulating FTO‐Mediated m6A Methylation of ELOB

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Bone marrow mesenchymal stem cells (BMSCs) promote tendon injury repair by enhancing tenocyte function and regulating the FTO/m6A/ELOB axis. Mechanistically, BMSCs lead to the upregulation of FTO and m6A modification, which subsequently suppresses ELOB expression.
Zhao‐Rong Dai, Guo‐Hua Luo, Yan‐Qiu Xie   +2 more
wiley   +1 more source

Prenatal Spectrum of COL2A1‐Related Spondyloepiphyseal Dysplasia Congenita: A Review and Two Case Reports

Prenatal Diagnosis, Volume 46, Issue 10, Page 1637-1647, September 2026.
ABSTRACT Objective To review the published literature on prenatal findings of COL2A1‐related SEDC, summarizing reported imaging and molecular variants, and to describe two additional prenatal cases evaluated at a tertiary referral center. Method A narrative review with a systematic search strategy was conducted to analyze prenatal imaging findings ...
López‐Rodríguez Larissa, León‐Madero Luis Felipe, Jiménez‐Chaidez Salvador, Gallardo‐Gaona Juan Manuel, Rodríguez‐Sibaja María Jose, Castañeda‐de‐la‐Fuente Angelica, Del Castillo‐Reyes Katia Alejandra, Yañez‐Felix Ana Lucia, Morales‐Dominguez Valeria, Borboa‐Olivares Héctor Jesús, Sevilla‐Montoya Rosalba   +10 more
wiley   +1 more source

hTERT Immortalization Stabilizes Human Umbilical Cord MSCs and Maintains Their Small Extracellular Vesicles With Preserved Immunomodulatory Activity and Primordial Follicle‐Activating Capacity

Aging Cell, Volume 25, Issue 9, September 2026.
hTERT immortalization stabilizes hUCMSC‐derived sEV function by alleviating cellular senescence and preserving young‐like cargo profiles. H11‐sEVs retain immunomodulatory activity, primordial follicle‐activating capacity, and ovarian protective effects.
Yating Chen, Wei Liu, Ying Tian, Xinyu Wang, Haonan Fan, Mingyu Yang, Feiyang Diao, Jing Li   +7 more
wiley   +1 more source

Evaluation of the clinical efficacy of using an inverted triangular cannulated compression screw in combination with positive or negative buttress reduction for the healing of femoral neck fractures

BMC Musculoskeletal Disorders
Objective We aimed to compare the clinical efficacy of inverted triangular cannulated compression screws combined with Gotfried positive or negative buttress reduction in the healing of femoral neck fractures. Methods Between October 2017 and March 2021,
Gang Wang, Cui Tang, Yong Tang, Rui Wang, Tugang Shen, Chundao Xu, Jian Yu, Gaokai Li   +7 more
doaj   +1 more source

Comparison of Acetabular Morphology Between Femoral Neck and Intertrochanteric Fractures

Objective: This study aimed to examine the correlation between acetabular morphology and fractures of the proximal femur. Methods: In this retrospective study, we examined patients who were admitted to our hospital between 2017 and 2021 due to ...
Mehmet Cenk Turgut, Erdem Şahin, Alperen Zeynel   +2 more
core   +1 more source

Breaking the Debilitating Cycle: Pathophysiology, Assessment, and Multimodal Intervention of Secondary Debilitation After Hip Fracture in Older Adults—A Narrative Review

Orthopaedic Surgery, Volume 18, Issue 9, Page 1785-1803, September 2026.
This article provides a comprehensive overview of the pathophysiological mechanisms underlying “secondary debilitation after hip fracture,” discusses the clinical application of risk assessment tools, and presents a phased, stepwise intervention strategy aimed at interrupting the “vicious cycle.” ABSTRACT Hip fractures pose a serious threat to the ...
Wenyang Xu, Fan Xu, Maoqiang Fan, Yao Liu, Zhe Song   +4 more
wiley   +1 more source

Femoral shortening in intertrochanteric fractures

, 2001
We compared 54 patients treated by a Medoff sliding plate (MSP) with 60 stabilised by a compression hip screw (CHS) in a prospective, randomised study of the management of intertrochanteric femoral fractures.
L. Ceder, A. Hauggaard, O. Olsson
core   +1 more source

Jumping on the moon as a potential exercise countermeasure

Experimental Physiology, Volume 111, Issue 9, Page 4073-4088, 1 September 2026.
Abstract The Moon's gravitational field strength (17% Earth's gravity) may facilitate the use of bodyweight jumping as an exercise countermeasure against musculoskeletal and cardiovascular deconditioning in reduced gravity settings. The present study characterised the acute physiological and kinetic responses to bodyweight jumping in simulated Lunar ...
Patrick Swain, Filipa Santos, Luke Hughes, Dan Gordon, Nick Caplan   +4 more
wiley   +1 more source

Nonanatomical reduction of femoral neck fractures in young patients with different Pauwels classifications: a retrospective study and finite element analysis

BMC Musculoskeletal Disorders
Background Previous studies have reported that positive buttress is as effective as anatomical reduction in treating young femoral neck fractures, but whether this effect is related to the Pauwels classification remains unclear. The purpose of this study
Binglang Xiong, Xuhan Cao, Cheng Zhang, Shaoyu Wang, Xudong Sun, Ziyan Guo, Qingwen Zhang, Zixing Bai, Weidong Sun   +8 more
doaj   +1 more source

Is an additional cannulated screw necessary for unstable femoral neck fractures with comminuted posteromedial cortex by femoral neck system (FNS) fixation? a biomechanical and clinical study

Frontiers in Bioengineering and Biotechnology
BackgroundThe purpose of this study was to explore the biomechanical property and clinical efficacy of femoral neck system (FNS) with an additional cannulated screws (CS) in the treatment of unstable femoral neck fracture (FNFs) with comminuted ...
Jixing Fan, Jixing Fan, Youliang Hao, Youliang Hao, Yuan Cao, Yuan Cao, Zengzhen Cui, Zengzhen Cui, Yang Lv, Yang Lv, Fang Zhou, Fang Zhou   +11 more
doaj   +1 more source