Results 61 to 70 of about 60,704 (235)

Simple Minimally Invasive Method to Reduce Valgus‐Impacted and Tilted Femoral Neck Fractures without Soft Tissue or Cartilage Injury: Radiological and Clinical Results

Orthopaedic Surgery, 2023
Objective This is a rare study comparing the radiological and functional outcomes of fixation after reduction with in situ fixation group using Femoral Neck System (FNS).
Seok‐Hyun Kweon, Joo‐Hyoun Song, Hyun Woo Park, Muhyun Kang, Young‐Wook Lim, Se‐Won Lee, Darshil Parikh, Seungbae Oh   +7 more
doaj   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Thyroid hormone status within the physiological range affects bone mass and density in healthy men at the age of peak bone mass [PDF]

, 2011
Context: The hormonal factors involved in the regulation of peak bone mass (PBM) in men have not been fully investigated. Apart from gonadal steroids and somatotropic hormones, thyroid hormones are known to affect bone maturation and homeostasis and are ...
Fiers, Tom, Goemaere, Stefan, Kaufman, Jean, Lapauw, Bruno, ROEF, GREET, Taes, Youri, Zmierczak, Hans-Georg   +6 more
core   +2 more sources

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Femoral neck nonunion: new classification used in total hip arthroplasty in elderly patients

Гений oртопедии, 2022
Introduction The risk of the femoral neck fracture nonunion is 48 % with avascular necrosis of the femoral head being reported in 42 % of cases. There are many classifications of acute intra-articular fractures of the proximal femur and there are no ...
Alexander N. Tsed, Nikita E. Mushtin, Anton V. Shmelev, Alexander K. Dulaev   +3 more
doaj   +1 more source

Common variants in FLNB/CRTAP, not ARHGEF3 at 3p, are associated with Osteoporosis in southern Chinese women [PDF]

, 2010
We performed an association study of five candidate genes within chromosome 3p14-25 in 1,080 Chinese female subjects. Polymorphisms in FLNB/CRTAP are associated with bone mineral density (BMD) in Chinese.
Huang, QY, Kung, AWC, Li, GHY
core   +2 more sources

Homozygous Achondroplasia With Long‐Term Survival: Growth Patterns, Medical Interventions, and Practice Implications

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Homozygous achondroplasia is widely considered perinatal lethal by the medical community. In this case series, we report two children from a single family with longer‐term survival. One child lived for 17 months and the other was 60 months at the time of publication.
Hannah Singerline, Jason Laufman, Kimberly Wallis, Michelle Merrill   +3 more
wiley   +1 more source

Comparison of Transverse Cancellous Lag Screw and Ordinary Cannulated Screw Fixations in Treatment of Vertical Femoral Neck Fractures

Orthopaedic Surgery, 2019
Objective To compare the clinical therapeutic effect of transverse cancellous lag screw (TCLS) fixations and ordinary cannulated screw (OCS) fixations for vertical femoral neck fractures.
Qiang Dong, Zhe Han, Yin‐Guang Zhang, Xiang Sun, Xin‐Long Ma   +4 more
doaj   +1 more source

Clinical observation and finite element analysis of cannulated screw internal fixation in the treatment of femoral neck fracture based on different reduction quality

Journal of Orthopaedic Surgery and Research, 2021
Objective Femoral neck fracture is one of the most common bone types. The effect of reduction quality on hip joint function and complications after screw internal fixation is not fully understood.
Gan Zhao, Ming Liu, Bin Li, Haizhong Sun, Biaofang Wei   +4 more
doaj   +1 more source

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

The Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen, Emma Sherratt, Philip Stott, Rachel Norris   +3 more
wiley   +1 more source