Results 91 to 100 of about 99,810 (350)

Postoperative Fall after the Use of the 3-in-1 Femoral Nerve Block for Knee Surgery: A Report of Four Cases

open access: yesJournal of Orthopaedic Surgery, 2008
We present a serious postoperative complication related to the use of femoral nerve block in 4 patients, each of whom fell and sustained further injury.
HDE Atkinson   +4 more
doaj   +1 more source

Comparison of continuous femoral nerve block with and without combined sciatic nerve block after total hip arthroplasty: a prospective randomized study

open access: yesOrthopedic Reviews, 2017
In association with the growing interests in pain management, several modalities to control postoperative pain have been proposed and examined for the efficacy in the recent studies.
Shoji Nishio   +6 more
doaj   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

open access: yesAdvanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang   +16 more
wiley   +1 more source

Injectable and In Situ Hydration‐Reinforced Hybrid Bone Cements for Accelerated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
To enable minimally invasive bone defect repair, an injectable and hydration‐reinforced bone cement (L‐PEGS/CPC) is designed through biomimetic reconstruction. The hydrophilic L‐PEGS organic phase provides abundant nucleation sites, synergizing with its porous architecture to accelerate CPC hydration, thereby endowing the composite with exceptional ...
Xing Chen   +7 more
wiley   +1 more source

The treatment of primary tumors of the femur with chemotherapy (if indicated), resection and reconstruction with an endoprosthesis [PDF]

open access: yes, 1985
The treatment protocol of 15 patients with a primary tumor of the femur, including osteosarcoma, malignant fibrous histiocytoma and chondrosar-coma is presented. All patients had been selected for resection and reconstruction with an endoprosthesis.
Göeken, L.N.H.   +10 more
core   +3 more sources

Identification and Mechanisms of Osteocyte Subsets Involved in the Pathological Progression of Osteoporosis

open access: yesAdvanced Science, EarlyView.
Osteocyte heterogeneity in bone remains poorly understood. This study identifies six distinct osteocyte subsets in mice, revealing a key subpopulation (BHR‐Ocys) that drives bone loss in osteoporosis. BHR‐Ocys promote osteoclast‐mediated resorption via a novel Sema5a‐Plxna1 signaling axis.
Zengxin Jiang   +8 more
wiley   +1 more source

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang   +18 more
wiley   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

open access: yesAdvanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li   +7 more
wiley   +1 more source

Neural regulation of cardiovascular response to exercise: role of central command and peripheral afferents [PDF]

open access: yes, 2014
During dynamic exercise, mechanisms controlling the cardiovascular apparatus operate to provide adequate oxygen to fulfill metabolic demand of exercising muscles and to guarantee metabolic end-products washout.
Crisafulli, A   +5 more
core   +4 more sources

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