Results 101 to 110 of about 501,110 (296)

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Comparison of continuous femoral nerve block with and without combined sciatic nerve block after total hip arthroplasty: a prospective randomized study

Orthopedic Reviews, 2017
In association with the growing interests in pain management, several modalities to control postoperative pain have been proposed and examined for the efficacy in the recent studies.
Shoji Nishio, Shigeo Fukunishi, Tomokazu Fukui, Yuki Fujihara, Shohei Okahisa, Yu Takeda, Shinichi Yoshiya   +6 more
doaj   +1 more source

Long-term results of a hydroxyapatite-coated femoral component in total hip replacement. A 15- to 21-year follow up study

, 2007
Between 1986 and 1991 we implanted 331 consecutive Furlong hydroxyapatite-coated femoral components of a total hip replacement in 291 patients. A cemented acetabular prosthesis was used in 217 hips and a hydroxyapatite-coated component in 114.
Rajaratnam, S.S., A. Tavakkolizadeh, R J Fletcher (13437510), Jack, C., George, M.D., A Tavakkolizadeh (16046336), Fletcher, R.J., S. S. Rajaratnam, C Jack (16046333), J. A. N. Shepperd, J A N Shepperd (16046342), Sheppard, J.A.N., C. Jack, Tavakkolizadeh, A., Hankins, M., M. Hankins, R. J. Fletcher, M Hankins (50557), M. D. George, S S Rajaratnam (16046330), M D George (16046339)   +20 more
core   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Postoperative Fall after the Use of the 3-in-1 Femoral Nerve Block for Knee Surgery: A Report of Four Cases

Journal of Orthopaedic Surgery, 2008
We present a serious postoperative complication related to the use of femoral nerve block in 4 patients, each of whom fell and sustained further injury.
HDE Atkinson, I Hamid, CM Gupte, RC Russell, JM Handy   +4 more
doaj   +1 more source

Diffusion tensor imaging and tractography of the sciatic and femoral nerves in healthy volunteers at 3T

Journal of Orthopaedic Surgery and Research, 2017
Background The aim was to clarify the normal fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of the sciatic and femoral nerves at the level of the hip joint and to visualize the neural tracts with diffusion tensor imaging (DTI).
Yasushi Wako, Junichi Nakamura, Yawara Eguchi, Shigeo Hagiwara, Michiaki Miura, Yuya Kawarai, Masahiko Sugano, Kento Nawata, Kensuke Yoshino, Yasunari Toguchi, Yoshitada Masuda, Koji Matsumoto, Takane Suzuki, Sumihisa Orita, Seiji Ohtori   +14 more
doaj   +1 more source

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto, Céline Huber, Clément Paya, Isabelle Audo, Nathalie Boddaert, Valérie Cormier‐Daire   +5 more
wiley   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Distal femoral resection

, 2011
This text is a general description of a distal femoral resection. Focus is on anatomical structures and muscle resection. Each femoral resection is different based on tumor biology, extension and tissue contamination.
Fuchs, B, Arteau, A
core  

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen, Li Gao, Xu Han, Yunyun Cao, Lanlan Zhang, Yi Wu, Xinrong Zhao, Wenjing Hu, Ruiyu Ma, Renyi Hua, Niu Li, Yanlin Wang, Jian Wang, Shuyuan Li   +13 more
wiley   +1 more source