Results 141 to 150 of about 93,984 (297)

Prenatal Exome Sequencing Analysis in Fetuses With Structural Anomalies: A Multicenter Prospective Cohort Study With Practical Implications

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the diagnostic value of prenatal exome sequencing (ES) integrated with copy number variant (CNV) and single nucleotide variant (SNV) analysis (ES‐CNV/SNV) in fetuses with structural anomalies following negative chromosomal microarray analysis (CMA) and karyotyping, and to delineate the practical challenges encountered ...
Yulin Jiang   +21 more
wiley   +1 more source

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

open access: yesPM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang   +6 more
wiley   +1 more source

A randomized controlled trial of iliopsoas plane block vs. femoral nerve block for hip arthroplasty. [PDF]

open access: yesBMC Anesthesiol, 2023
Wang CG   +5 more
europepmc   +1 more source

Development of a Grasshopper‐Leg‐Inspired Back‐Type Exoskeleton for the Reduction of Muscle Activation During Stoop Activities

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Farmers frequently suffer from musculoskeletal disorders, particularly lower back pain (LBP), mainly due to occupational ergonomic factors such as repetitive stooping and lifting. This study proposes using an exoskeleton to reduce LBP risk by providing external torque to the hip joints.
Dang Khanh Linh Le, Wei Chih Lin
wiley   +1 more source

Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases

open access: yesSmall Science, EarlyView.
This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li   +7 more
wiley   +1 more source

2D Boron Nanoplatelets as a Multifunctional Additive for Osteogenic, Gram‐Negative Antimicrobial and Mechanically Reinforcing Bone Repair Scaffolds

open access: yesSmall Science, EarlyView.
An ideal bone scaffold will enhance osteogenesis, angiogenesis, and neurogenesis, while preventing inflammation, infection, and stiffness mismatch. 2D materials unlock diverse properties arising from the nanoplatelet morphology, while simultaneously leveraging intrinsic material properties .
Jack Maughan   +9 more
wiley   +1 more source

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