Results 51 to 60 of about 33,837 (300)

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Local infiltration analgesia versus femoral nerve block in total knee arthroplasty: A meta-analysis [PDF]

, 2015
IntroductionLocal infiltration analgesia (LIA) and femoral nerve block (FNB) are both used for the pain management after total knee arthroplasty (TKA). Controversy still remains regarding the optimal technique for pain relief in patients undergoing TKA ...
Yun, X.-D., Yin, X.-L., Jiang, J., Teng, Y.-J., Dong, H.-T., An, L.-P., Xia, Y.-Y.   +6 more
core   +2 more sources

Ultra‐Thin Soft Pneumatic Actuation for Minimally Invasive Neural Interfacing

Advanced Materials Technologies, EarlyView.
Parylene C is a common polymer in bioelectronics, favored for its biological and chemical inertness. However, this makes bonding layers of Parylene C together very challenging. Here it is a laser to selectively weld layers of Parylene C to create high‐pressure fluidic actuation devices.
Lawrence Coles, Joe G. Troughton, Alejandro Carnicer‐Lombarte, George G. Malliaras, Christopher M. Proctor   +4 more
wiley   +1 more source

The Effects of the Pericapsular Nerve Group Block on Postoperative Pain in Patients with Hip Fracture: A Multicenter Study

Diagnostics
Background: An adequate early mobilization followed by an effective and pain-free rehabilitation are critical for clinical and functional recovery after hip and proximal femur fracture.
Carmine Iacovazzo, Rosario Sara, Pasquale Buonanno, Maria Vargas, Antonio Coviello, Roberta Punzo, Vincenzo Maffei, Annachiara Marra   +7 more
doaj   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Dose-dependent neurotoxicity caused by the addition of perineural dexmedetomidine to ropivacaine for continuous femoral nerve block in rabbits

Journal of International Medical Research, 2019
Objective This study was designed to evaluate the neurotoxicity of dexmedetomidine combined with ropivacaine for continuous femoral nerve block in rabbits.
Hai-Li Wang, Guang-Ying Zhang, Wei-Xin Dai, Li-Pei Shu, Qiu-Feng Wei, Ruo-Fang Zheng, Cheng-Xin Lin   +6 more
doaj   +1 more source

Arthroscopic medial meniscus trimming or repair under nerve blocks: Which nerves should be blocked?

Saudi Journal of Anaesthesia, 2016
Background: This study aimed to determine the role of the sciatic and obturator nerve blocks (in addition to femoral block) in providing painless arthroscopic medial meniscus trimming/repair.
A M Taha, A M Abd-Elmaksoud
doaj   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Ultrasound Controlled‐Release Hydrogel Promotes Diabetic Wound Healing via Neuroimmune Modulation and Synergistic ROS Scavenging

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive hydrogel (MCF@CA) that co‐delivers a neuropeptide (CGRP) and a ROS‐scavenging manganese porphyrin to diabetic wounds. The system restores neuro‐immune communication, reprograms macrophages toward an anti‐inflammatory phenotype, and clears excess ROS, thereby accelerating wound closure and promoting mature ...
Mofan Li, Mengxin Wang, Haonan Wang, Yang Sun, Yongyue Zhang, Shuyu Xu, Tianjiao Zhang, Shiti Shama, Xiaolong Liang, Shumin Wang   +9 more
wiley   +1 more source

Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits [PDF]

, 2008
Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits
Hausdorf, J., Maier, M., Milz, S., Pautke, C., Schmitz, C., Tischer, T., Weiler, C.   +6 more
core   +1 more source