Results 61 to 70 of about 534,638 (361)

Critical-Sized Bone Defects: Sequence and Planning. [PDF]

, 2017
Bone defects associated with open fractures require a careful approach and planning. At initial presentation, an emergent irrigation and debridement is required.
Abell, Apostle, Benson, Blum, Bosse, Breccia, Brewster, Brumback, Burston, Carver, D'Alleyrand, Dedmond, Dellinger, Dumbre Patil, Fischer, Fleming, Gerken, Gustilo, Gustilo, Henley, Hoff, Jenkinson, Johnson, Kao, Kirkup, Lack, Lee, Lee, Luchette, Mnif, Mohammad, Morelli, Moues, Murray, Palmer, Papakostidis, Patzakis, Patzakis, Pollak, Redfern, Rodriguez, Smith, Stannard, Templeman, Tornetta, Webb, Yaremchuk, Zalavras   +47 more
core   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Comparing Outcomes Between the Over-the-Top and All-Epiphyseal Techniques for Physeal-Sparing ACL Reconstruction: A Narrative Review. [PDF]

, 2019
A variety of techniques are used for physeal-sparing anterior cruciate ligament (ACL) reconstruction; however, there is no clear consensus on the ideal surgical technique, the frequency of complications, and how to best avoid growth disturbance.
Feeley, Brian T, Pandya, Nirav K, Wong, Stephanie E   +2 more
core  

Change-of-direction speed and aerobic fitness could influence academy graduation in law enforcement recruit [PDF]

, 2012
BACKGROUND: Technical advancements have produced many challenges to intramedullary implants for unstable pertrochanteric fractures. Helical blade fixation of the femoral head has the theoretical advantages of higher rotational stability and cutout ...
Lockie, Robert G., Balfany, Katherine, Bloodgood, Ashley M., Stierli, Michael, Dulla, Joe, Dawes, Jay, Orr, Rob Marc   +6 more
core   +1 more source

Biodegradable Zinc‐Based Alloys for Guided Bone Regeneration Membranes: Feasibility, Current Status, and Future Prospects

Advanced Science, EarlyView.
Recent research has shown that biodegradable metals based on zinc (Zn) may be used as guided bone regeneration (GBR) membrane materials. This study examines their viability from the standpoints of material science and biology, reports on the state of research on Zn‐based GBR membranes, and suggests specific development plans based on the potential and ...
Kai Chen, Ping Li, Qiang Guan, Xuenan Gu, Li Zhao, Linjun Huang, Chenyang Huang, Yu Qin, Chunhao Yu, Ting Zhang, Hejia Li, Yongcan Huang, Yufeng Zheng   +12 more
wiley   +1 more source

Challenges in managing ipsilateral femoral neck and shaft fracture at Mission Hospital

CHRISMED Journal of Health and Research, 2016
Rarity of ipsilateral femoral neck and shaft fracture qualifies it as a difficult fracture to diagnose as well as treat. No ideal treatment option has been defined, and no ideal implant has been assigned for the management of such fractures.
Deeptiman James
doaj   +1 more source

Augmented Stability in Leaving Original Internal Fixation with Multidimensional Cross Locking Plate through Mini‐Open Femoral Anterior Approach for Aseptic Femoral Shaft Nonunion: A Retrospective Cohort Study

Orthopaedic Surgery, 2023
Objective Aseptic femoral shaft nonunion constitutes approximately 1%–10% of all femoral shaft fractures treated with intramedullary nail (IMN) fixation, possibly attributable to the lack of anti‐rotational stability. Although a lateral locking plate (LP)
Taoguang Wu, Wei Zhang, Zuhao Chang, Zhengguo Zhu, Lijun Sun, Peifu Tang, Hua Chen   +6 more
doaj   +1 more source

Denosumab Reduces Cortical Porosity of the Proximal Femoral Shaft in Postmenopausal Women With Osteoporosis

Journal of Bone and Mineral Research, 2016
Hip fractures account for over one‐half the morbidity, mortality, and cost associated with osteoporosis. Fragility of the proximal femur is the result of rapid and unbalanced bone remodeling events that excavate more bone than they deposit, producing a ...
R. Zebaze, C. Libanati, M. McClung, J. Zanchetta, D. Kendler, A. Høiseth, Andrea T Wang, A. Ghasem-Zadeh, E. Seeman   +8 more
semanticscholar   +1 more source

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

Advanced Science, EarlyView.
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan, Yi Ran, Hong Pan, Qinnan Yan, Wenjing Zhang, Bo Zhou, Pengzhi Xu, Rongdong Liao, Haipeng Xue, Will Jiang, Tailin He, Qingyun Jia, Lei Qin, Francis Y Lee, Di Chen, Chuanju Liu, Guozhi Xiao   +16 more
wiley   +1 more source

Virulence‐Selective Trap–Capture–Kill Antibacterial Nanostructures With Immune–Metabolic Regulation for Treating Implant‐Associated Infections

Advanced Science, EarlyView.
A virulence‐selective antibacterial system based on fascaplysin derivative 14‐modified TiO2 nanostructure (F‐14‐TNA) is developed for treating implant‐associated infections. F‐14‐TNA selectively traps hyperpathogenic bacteria via chemotaxis, captures them electrostatically, and kills them via reactive oxygen species‐mediated pathways.
Xiaodong Hu, Jiaqi Zhong, Yujiong Chen, Botao Liu, Tianyu Du, Weilai Zhu, Minzhe Zheng, Hongze Liang, Jiahua Ni, Zhaoxiang Peng   +9 more
wiley   +1 more source