Results 101 to 110 of about 27,538 (215)

HSD17B7 Counters Bone Loss in Estrogen Deficiency via Estrogen Receptor Stabilization and Mediates the Effect of Raloxifene

MedComm, Volume 7, Issue 2, February 2026.
In this study, we identified a previously unrecognized function of HSD17B7 as an ERα‐binding protein that serves as a coactivator to influence trabecular bone mass in estrogen deficiency. Specifically, deleting HSD17B7 in myeloid cells enhanced the number of osteoclasts and decreased trabecular bone mass post‐OVX, compared with control OVX, mirroring ...
Junyue Zhang, Yiping Song, Jeong‐Hyun Koo, Si Chen, Kyu Yun Jang, Sun‐Jung Yoon, Jung Ryul Kim, Young Jae Moon   +7 more
wiley   +1 more source

COMPARISON OF SOLID VERSUS CANNULATED INTERLOCK INTRAMEDULLARY NAILS FOR MANAGEMENT OF ISOLATED FEMORAL SHAFT FRACTURES

Journal of University Medical & Dental College, 2018
: OBJECTIVE: Compare the frequency of post-operative surgical site infection of solid interlock intramedullary nail with cannulated open interlock intramedullary nail for management of isolated femoral fracture.
M.Abdul Rehman Yaseen, Mazhar Mehmood, Muhammad Javaid Iqbal   +2 more
doaj  

Ipsilateral proximal and shaft femoral fractures

Chinese Journal of Traumatology, 2017
Purpose: To study the management and evaluate anatomical and functional outcomes of patients with ipsilateral proximal and shaft femoral fractures. Methods: A retrospective, descriptive and analytic study lasted for ten years and a half ranging from ...
Eric Lawson, Soumaila Madougou, Pascal Chigblo, Gildas Quenum, Abdourahmane Ouangré, Fiacre Tidjani, Oswald Goukodadja, Aristote Hans-Moevi Akué   +7 more
doaj   +1 more source

A 50‐year perspective on the use and potential of artiodactyl calcanei in bone adaptation studies

Biological Reviews, Volume 101, Issue 1, Page 437-485, February 2026.
ABSTRACT Sheep and deer calcanei are important models for studying cortical (compact) and trabecular (cancellous) bone adaptation because they are amenable to direct strain measurement (due to lack of surrounding muscles), experience relatively simple/unidirectional bending, exhibit osteon remodelling, and have the most pronounced regional variations ...
John G. Skedros
wiley   +1 more source

Avascular Necrosis and Minimal Trauma Fractures in Telomere Biology Disorders

Clinical Genetics, Volume 109, Issue 2, Page 286-293, February 2026.
Avascular Necrosis (AVN) and Minimal Trauma Fractures (MTF) cause significant morbidity in people with Telomere Biology Disorders (TBDs). They occur more frequently in young patients and in those with autosomal recessive (AR) or X‐linked recessive (XLR) than in autosomal dominant (AD) genotypes.
Arman M. Niknafs, Neelam Giri, Marena R. Niewisch, Sharon A. Savage   +3 more
wiley   +1 more source

Double Reverse Traction‐Assisted Versus Traditional Freehand Closed Reduction With Hexapod External Fixator in Treating Open Tibial Shaft Fractures: A Retrospective Study

Orthopaedic Surgery, Volume 18, Issue 2, Page 279-288, February 2026.
Double reverse traction‐assisted apparatus. ABSTRACT Objective Open tibial shaft fractures (OTSFs) pose significant therapeutic challenges due to high‐energy trauma, extensive soft tissue damage, and contamination risks, complicating fracture stabilization and increasing infection rates.
Zhiming Zhao, Yuanyuan Geng, Bowen Shi, Jian Chen, Yabin Liu, Chengkuo Cai, Guoqi Ji, Weiguo Xu   +7 more
wiley   +1 more source

Use of controlled nail dynamization technique for femoral shaft hypertrophic nonunion

Frontiers in Surgery
BackgroundFemoral nonunion after intramedullary nailing (IMN) of a diaphyseal long bone fracture is a severe complication that requires effective management. The IMN dynamization has been used to treat hypertrophic nonunions previously.
Qian Wu, Qi Wang, XueCheng Sun, Jun Liu, Gang Zhao, Ping Yu   +5 more
doaj   +1 more source

The Socioeconomic consequences of femoral shaft fracture for patients in Malawi. [PDF]

Malawi Med J, 2023
Mody KS, Wu HH, Chokotho LC, Mkandawire NC, Young S, Lau BC, Shearer D, Agarwal-Harding KJ.   +7 more
europepmc   +1 more source

Kidney disease impairs tendon function in rats

The Journal of Physiology, Volume 604, Issue 3, Page 1113-1136, 1 February 2026.
Abstract figure legend This study demonstrates for the first time that tendon strength is reduced in a rodent model of chronic kidney disease (8 weeks of 0.25% adenine feeding) and confirms concurrent dysfunction in muscle and bone. These findings provide novel characterization of multiple tissues, paving the way for future investigations into the ...
Christopher M. T. Hayden, Natalie K. Gilmore, Benjamin Osipov, Sarah E. Brashear, Marc Gorge, Juang‐Yu Jen, Lucas R. Smith, Blaine A. Christiansen, Baback Roshanravan, Keith Baar   +9 more
wiley   +1 more source

Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report [PDF]

, 2018
Summary: This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this association, but retrospective phase III trial ...
Bouxsein, M., Cooper, C., Kanis, J., Napoli, N., Papapoulos, S., Reginster, J.-Y, Rizzoli, R., Åkesson, K.   +7 more
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