Results 121 to 130 of about 137,379 (339)

Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis

open access: yesAdvanced Science, EarlyView.
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart   +4 more
wiley   +1 more source

Duplication unilateral femoral vein

open access: yesBangladesh Journal of Medical Science, 2015
Background: The purpose of this paper is to describe a case of duplication of unilateral femoral vein, with a complete extension of duplicated veins with similar diameters which is an uncommon condition, noticed in fewer than 10% of lower limb. The venous anatomy is highly variable, only 1/6 patients are exempt of these anomalies.
openaire   +2 more sources

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

open access: yesAdvanced Science, EarlyView.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li   +5 more
wiley   +1 more source

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

open access: yesAdvanced Science, EarlyView.
This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan   +7 more
wiley   +1 more source

Right ventricular outflow tract stenting : effective palliation for Fallot’s tetralogy [PDF]

open access: yes, 2015
Traditionally, the management of infants with Fallot’s tetralogy (TOF) with excessively reduced pulmonary flow and cyanosis has been palliation until or unless complete repair is feasible.
Bugeja, Justine   +2 more
core  

Diagnosis of Deep Vein Thrombosis and Fractures of Femoral Neck [Summary] [PDF]

open access: bronze, 1972
E S Field   +3 more
openalex   +1 more source

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
The aberrant adenosine metabolism leads to chemoresistance and immunosuppressive microenvironment. A versatile albumin‐polyplexes conjugated nanoparticle B‐PDEA@CPA is prepare for the codelivery of gemcitabine and siCD39. The nanoparticle releases gemcitabine‐loaded albumin upon microenvironment to achieve promoted penetration and cellular uptake ...
Hongrui Fan   +10 more
wiley   +1 more source

Long-term results of infragenicular bypasses with autogenous vein originating from the distal superficial femoral and popliteal arteries [PDF]

open access: bronze, 1988
Mark S. Rosenbloom   +7 more
openalex   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li   +5 more
wiley   +1 more source

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