Results 231 to 240 of about 205,023 (305)

Development of a machine learning-based model for predicting the functional outcome of patients with proximal femur fractures. [PDF]

Sci Rep
Nozawa K, Maki S, Tanaka I, Inage K, Shiga Y, Inoue M, Eguchi Y, Furuya T, Nakamura J, Hagiwara S, Kawarai Y, Ohtori S, Orita S.   +12 more
europepmc   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Parosteal Lipoma of the Thigh: A Report of a Rare Case and Review of the Literature. [PDF]

Cureus
Shah KY, Phatak S, Mitra K, Onkar P, Pantawane PB.   +4 more
europepmc   +1 more source

Statistical consequences of using bone mineral density to pair cadaver femurs in comparative ex vivo hip fracture studies

, 2014
Trude Basso, Jomar Klaksvik, Olav A. Foss   +2 more
openalex   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Limb salvage in multiple revision total knee arthroplasty using customised implants: When sleeves and cones are no longer an option. [PDF]

J Exp Orthop
Donner S, Gwinner C, Haffer H, Perka C, Kirschbaum S.   +4 more
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Biomechanical analysis of anatomical intramedullary nails and proximal femoral anti-rotation-II intramedullary nails for the treatment of unstable intertrochanteric fractures (AO type 31-A2.2) in older patients. [PDF]

J Orthop Surg Res
Ma XW, Chen J, Hu Y, Fan ZR.
europepmc   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Shape, Size and Bilateral Asymmetry of the Humerus and Femur in the Common Swift (<i>Apus apus</i>). [PDF]

Animals (Basel)
Bilgiç EB, Pasicka E, Korkmazcan A, Manuta N, Çakar B, Günay E, Gün G, Gündemir O.   +7 more
europepmc   +1 more source