Results 251 to 260 of about 489,827 (389)

BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration

open access: yesAdvanced Science, EarlyView.
A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou   +8 more
wiley   +1 more source

Surgical Timing and Postoperative Outcomes in Distal Femur Fractures: Does Early Intervention Matter? [PDF]

open access: yesGeriatr Orthop Surg Rehabil
Onizuka N   +4 more
europepmc   +1 more source

What makes an accurate and reliable subject-specific finite element model? A case study of an elephant femur

open access: yesJournal of the Royal Society Interface, 2014
O. Panagiotopoulou   +4 more
semanticscholar   +1 more source

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

open access: yesAdvanced Science, EarlyView.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu   +17 more
wiley   +1 more source

Transtrochanteric Transverse Fracture of Proximal Femur in Pediatric Child: A Rare Variant: Case Report and Surgical Management. [PDF]

open access: yesJ Orthop Case Rep
Rohinth S   +4 more
europepmc   +1 more source

Healing Delayed But Generally Reliable After Bisphosphonate-associated Complete Femur Fractures Treated with IM Nails

open access: yesClinical Orthopaedics and Related Research, 2014
K. Egol   +4 more
semanticscholar   +1 more source

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

open access: yesAdvanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu   +5 more
wiley   +1 more source

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

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