Results 261 to 270 of about 476,865 (415)

Identification of NIBAN2‐Regulated RUNX2 Alternative Splicing Presents Novel Strategies for Antagonizing Osteoporosis

open access: yesAdvanced Science, EarlyView.
NIBAN2 interacts with the HNRNPU‐cored spliceosome complex and alters its components to regulate the alternative splicing of RUNX2, which ultimately cause an increase in functional RUNX2 (nuclear localization sequence complete) but a decrease in dysfunctional Runx2 (exon 6‐exclusive) isoforms to reinforce osteoblast differentiation.
Sheng Zhang   +9 more
wiley   +1 more source

Expanding the clinical spectrum associated with the PACS1 p.Arg203Trp mutational hot‐spot: Two additional Italian patients

open access: yes, 2023
American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 284-288, January 2023.
Lucia Pia Bruno   +11 more
wiley   +1 more source

The Gollop-Wolfgang Complex: A Case Report. [PDF]

open access: yesPediatr Rep
Kim JB   +9 more
europepmc   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

open access: yesAdvanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi   +12 more
wiley   +1 more source

Fracture-Related Infection of the Proximal Femur - Diagnostics and Treatment. [PDF]

open access: yesGeriatr Orthop Surg Rehabil
Riedl M   +6 more
europepmc   +1 more source

Reversible High‐Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation

open access: yesAdvanced Science, EarlyView.
A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Chaojie Shi   +9 more
wiley   +1 more source

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