Results 71 to 80 of about 487,569 (388)

A Systematic Review and Meta-Analysis of Ilizarov Methods in the Treatment of Infected Nonunion of Tibia and Femur

PLoS ONE, 2015
Background Infected nonunion of tibia and femur are common in clinical practice, however, the treatment of these diseases has still been a challenge for orthopaedic surgeons.
P. Yin, Qiunan Ji, Tongtong Li, Jiantao Li, Zhirui Li, Jian‐heng Liu, Guoqi Wang, Song Wang, Lihai Zhang, Z. Mao, P. Tang   +10 more
semanticscholar   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

A comparison of cortical and trabecular bone from C57 Black 6 mice using Raman spectroscopy [PDF]

, 2009
Peer ...
Aspden, Richard M., Gibson, Iain R., Goodyear, Simon R., Skakle, Jan, Wells, Richard P. K.   +4 more
core   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

Advanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong, Ji‐Young Yoon, Junyong Ahn, Byunghak Lee, Sung‐Min Park, Jae‐Heon Kim, Buuvee Bayarkhangai, Yu Jin Kim, Sak Lee, Jonathan C. Knowles, Moon‐Young Kim, DongJun Lee, Sang‐Hoon Rhee, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee   +15 more
wiley   +1 more source

Outcomes of multiple and combined bone injuries of lower limbs treated with half-pin fixator

Гений oртопедии, 2018
Objective To review outcomes of lower limb injuries repaired with half-pin fixator. Material and methods The study included 28 patients with fractured femur and tibia due to multiple and combined injuries treated with half-pin fixator of the own ...
Fakhriddin B. Salokhiddinov, Murodulla Iu. Karimov, Kirill P. Tolochko   +2 more
doaj   +1 more source

Popliteus impingement after TKA may occur with well-sized prostheses [PDF]

, 2016
To determine the mechanisms and extents of popliteus impingements before and after TKA and to investigate the influence of implant sizing. The hypotheses were that (1) popliteus impingements after TKA may occur at both the tibia and the femur, and (2 ...
Bonnin, Michel, de Kok, Arnoud, Saffarini, Mo, Van Der Straeten, Catherine, Van Hoof, Tom, Verstraete, Matthias, Victor, Jan   +6 more
core   +1 more source

Infected nonunion of tibia and femur treated by bone transport

Journal of Orthopaedic Surgery and Research, 2015
ObjectiveThe objective of this study was to evaluate the effectiveness of the treatment of infected nonunion of tibia and femur by bone transport.Material and methodsWe retrospectively reviewed 110 patients with infected nonunion of tibia and femur ...
P. Yin, Lihai Zhang, Tongtong Li, Licheng Zhang, Guoqi Wang, Jiantao Li, Jian‐heng Liu, Jianfeng Zhou, Qun Zhang, P. Tang   +9 more
semanticscholar   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source