Results 61 to 70 of about 19,494 (244)

Economic Evaluation of the Use of FeNO for the Diagnosis and Management of Asthma Patients in Primary Care in Sweden

ClinicoEconomics and Outcomes Research, 2021
Josep Darbà,1 Meritxell Ascanio,2 Jörgen Syk,3– 5 Kjell Alving4 1Department of Economics, Universitat de Barcelona, Barcelona, Spain; 2BCN Health Economics & Outcomes Research, S.L., Barcelona, Spain; 3Department of Neurobiology ...
Darbà J, Ascanio M, Syk J, Alving K
doaj  

Small Airway Dysfunction Measured by Impulse Oscillometry and Fractional Exhaled Nitric Oxide Is Associated With Asthma Control in Children

Frontiers in Pediatrics, 2022
BackgroundImpulse oscillometry (IOS) and fractional exhaled nitric oxide (FeNO) are sensitive and non-invasive methods to measure airway resistance and inflammation, although there are limited population-based studies using IOS and FeNO to predict asthma
Liang-Mei Lin, Yu-Jun Chang, Kuender D. Yang, Kuender D. Yang, Ching-Hsiung Lin, Ching-Hsiung Lin, Ching-Hsiung Lin, Ching-Hsiung Lin, Jien-Wen Chien, Jien-Wen Chien, Jun-Kai Kao, Jun-Kai Kao, Jun-Kai Kao, Jun-Kai Kao, Jun-Kai Kao, Ming-Sheng Lee, Tsay-I Chiang, Ching-Yuang Lin, Yi-Giien Tsai, Yi-Giien Tsai, Yi-Giien Tsai, Yi-Giien Tsai   +21 more
doaj   +1 more source

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

Allergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić, Stephan C. Flory, Claudia C. V. Lang, Emma C. Widmer, Alexandra Chabot, Johannes M. Schmid, Tobias Andermatt, David Melillo, Bjarke Hviid‐Vyff, Maibritt Mardahl, Peter Schmid‐Grendelmeier, Thomas M. Kündig, Hans Jürgen Hoffmann, Pål Johansen   +13 more
wiley   +1 more source

The impact of fraction of exhaled nitric oxide measurements in patients with asthma exacerbation

Zdravniški Vestnik, 2011
BACKGROUND Fraction of exhaled nitric oxide measurements (FENO) is accessible, a fast, non- invasive, highly repeatable test for determining eosinophilic airway inflammation.PURPOSEThe objective of this prospective study is to determine the structure of ...
Majda Drnovšek Kaljanac
doaj  

The Effect of Adiposity Markers on Fractional Exhaled Nitric Oxide (FeNO) and Pulmonary Function Measurements

International Journal of General Medicine, 2020
Noor Al Khathlan,1 Ayad Mohammed Salem2 1Respiratory Care Department, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal ...
Al Khathlan N, Salem AM
doaj  

Balanço de nitrogênio, degradabilidade de aminoácidos e concentração de ácidos graxos voláteis no rúmen de ovinos alimentados com feno de Stylosanthes guianensis Nitrogen balance, amino acid degradability and volatile fatty acid concentration in the rumen of sheep fed Stylosanthes guianensis hay

Revista Brasileira de Zootecnia, 2002
Foram utilizados sete ovinos alimentados com feno de S. guianensis para avaliar a degradabilidade ruminal dos aminoácidos, o balanço nitrogenado e as concentrações de ácidos graxos voláteis (AGVs) no rúmen. A técnica de sacos de náilon foi empregada para
Márcio Machado Ladeira, Norberto Mario Rodriguez, Iran Borges, Lúcio Carlos Gonçalves, Eloísa de Oliveira Simões Saliba, Lídia Ferreira Miranda   +5 more
doaj   +1 more source

Assessing the suitability of Fractional Exhaled Nitric Oxide (FENO) cut-off ranges for aboriginal and/or Torres Strait Islander children and young adults

, 2018
Introduction/Aim Fractional exhaled nitric oxide (FeNO) is used as a non‐invasive measure of eosinophilic airway inflammation. It is unknown how appropriate the recommended FeNO cut‐off ranges are for Aboriginal and/or Torres Strait Islander patients ...
Chang, A, Mcelrea, M, Petsky, H, Blake, T, Chatfield, M   +4 more
core   +1 more source

Nasal Epithelial Immune Signatures Are Associated With Age‐Dependent Asthma Trajectories in Early Life

Allergy, EarlyView.
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth, Sabina Illi, Helen Charles, Madlen Oelsner, Amr A. Gabr, Ulrich M. Zissler, Anna Erb, Martin Feuerherd, Felix Drost, Maren Büttner, Benjamin Schubert, Nicole Maison, Jimmy Omony, Markus Weckmann, Ruth Grychtol, Anna‐Maria Dittrich, Svenja Foth, Chrysanthi Skevaki, Tobias Trojan, Silke van Koningsbruggen‐Rietschel, Gesine Hansen, Thomas Bahmer, Klaus F. Rabe, Folke Brinkmann, Matthias Volkmar Kopp, Ulrike Protzer, Adam M. Chaker, Bianca Schaub, Erika von Mutius, Carsten B. Schmidt‐Weber, the ALLIANCE Study Group as part of the German Center for Lung Research (DZL), Mira Bürk, Sybille Contento, Markus Ege, Kristina Gottschau, Silvia Gschwendtner, Alexander Hose, Lena Lagally, Michael Schloter, Lena Ullemeyer, Esther Zeitlmann, Mustafa Abdo, Heike Biller, Karoline I. Gaede, Clara Haug, Nikolas Jacobs, Anne‐Marie Kirsten, Inke R. König, Lea Kronziel, Gyde Nissen, Frauke Pedersen, Loana Pennerd, Isabell Ricklefs, Vera Veith, Henrik Watz, Marie Bickes, Mifflin‐Rae Calvero, David S. DeLuca, Svenja Gaedcke, Anika Habener, Christine Happle, Adan Chari Jirmo, Bin Liu, Lennart Riemann, Nicolaus Schwerk, Inga Jerrentrup, Harald Renz, Stefanie Weber, Miguel A. Alejandre Alcazar, Samira Blau, Ernst Rietschel, Jan‐Christoph Thomassen   +71 more
wiley   +1 more source