Results 321 to 330 of about 188,238 (387)

The Impact of Vatinoxan on the Concentrations of Medetomidine, Midazolam, and Fentanyl in Central Nervous System After Subcutaneous Co‐Administration in Rats

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Our aim was to investigate whether vatinoxan, a peripherally acting alpha2‐adrenoceptor antagonist, would affect the concentrations of medetomidine, midazolam, and fentanyl in the central nervous system after subcutaneous co‐administration. Twelve healthy male Wistar rats, aged between 13 and 15 weeks, were used in this study.
Juhana Honkavaara, Emily Lindh, Anna Meller, Karoliina Alm, Marja R. Raekallio, Pernilla Syrjä   +5 more
wiley   +1 more source

Estimates of Illicit Opioid Use in the US.

JAMA Health Forum
Powell D, Jacobson M.
europepmc   +1 more source

A Randomized, Blinded, Placebo‐Controlled Crossover Study of the Pharmacokinetics and Pharmacodynamics of Naloxone, Naltrexone, and Nalmefene in Methadone‐Sedated Working Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT A randomized, blinded, placebo‐controlled crossover study was performed with eight professional working dogs to evaluate the pharmacokinetics and pharmacodynamics of three opioid reversal agents. Following sedation with 1 mg kg−1 methadone HCl IV, dogs were randomly assigned to receive naloxone, naltrexone, or nalmefene at 0.1 mg kg−1 IM, or ...
Travis Mills, Mary A. Robinson, Ciara Barr, Darko Stefanovski, Youwen You, Rachel Proctor, Kasey Seizova, Amritha Mallikarjun, Cynthia M. Otto   +8 more
wiley   +1 more source

Initiation and Dosing of Extended-Release Buprenorphine: A Narrative Review of Emerging Approaches for Patients Who Use Fentanyl. [PDF]

Subst Abuse Rehabil
Lee KW, Mead A, Ghauri I, Hollett B, Drolet M, Kozicky JM.   +5 more
europepmc   +1 more source

Gastrointestinal Electrical Stimulation as Prevention of Postoperative Ileus—A Blinded Randomized Controlled Porcine Trial

Neurogastroenterology &Motility, EarlyView.
In this animal study, direct postoperative electrical stimulation of the sigmoid colon shortened the length of postoperative ileus in an animal model. ABSTRACT Introduction Postoperative ileus (POI) is a condition characterized by a transient cessation of gastrointestinal function caused by surgical trauma and represents a clinical challenge after ...
Anne Kraushaar Martensen, Dennis Moegltoft Poulsen, Frederik Ehlern, Christina Brock, Jonas Amstrup Funder   +4 more
wiley   +1 more source

Optimizing Intrathecal Opioid Strategies for Cesarean Section: A Comprehensive Narrative Review of Pharmacology, Clinical Outcomes, and Safety. [PDF]

Cureus
Moisa RC, Negrut N, Botea MO, Bodog TM, Moisa CCM, Thomas TC, John HT.   +6 more
europepmc   +1 more source

Effects of Noninvasive Respiratory Support on Ventilation Distribution During Spontaneous Breathing Sedation in Preschool/School‐Aged Children: An Electrical Impedance Tomography Study

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Procedural sedation interferes with respiratory dynamics in pediatric patients. It reduces lung compliance, causing the closing volume to exceed the functional residual capacity, which can result in airway collapse, atelectasis, and periods of silent desaturation.
Giovanna Chidini, Tiziana Marchesi, Stefano Scalia Catenacci, Gaetano Florio, Giorgio Conti, Stefano Lanni, Giovanni Filocamo, Francesca Patria, Marta Guerrini, Gregorio Milani, Giacomo Grasselli   +10 more
wiley   +1 more source

"You take care of people, people will take care of you": Moral Economies and an Unpredictable Drug Market. [PDF]

PLoS One
Gould EE, Ganesh SS, DiMario AJ, Huh J, Bluthenthal RN, Ceasar RC.   +5 more
europepmc   +1 more source

\u3cem\u3eColby v. Union Sec. Ins. Co\u3c/em\u3e: Defining the Risk of Relapse into Substance Abuse as a Current Disability [PDF]

, 2014
Lowe, Lindsay
core   +1 more source

Using a Patient‐Reported Outcome (PRO) Questionnaire to Assess Postoperative Care Following Pediatric Outpatient Surgery

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction In recent years, there has been a marked rise in the incidence of pediatric day surgery across Western countries. As postoperative recovery transitions to the home environment, it is incumbent on healthcare systems to develop methods for patient follow‐up and caregiver support.
Hjördis Osk Atladottir, Anne Treschow Phillipsen, Karen Arnt Krøyer, Anne Gade Jensen, Liv Marit Valen Schougaard, Peter Ahlburg   +5 more
wiley   +1 more source