Results 151 to 160 of about 5,308,940 (279)

Prevalence and Spectrum of Chronic Liver Disease Among Patients Seeking Health Care in Ghana

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background Chronic liver diseases (CLD) leading to liver fibrosis and cirrhosis are a major cause of morbidity and mortality in sub‐Saharan Africa and pose a significant burden on its health care systems. We aimed to elucidate the prevalence of fibrosis/cirrhosis in patients seeking health care in Kumasi, Ghana, and its underlying aetiologies.
Felix Lehmann, Alexander Killer, Sarah Wels, Stefan Schmiedel, Richard Odame Phillips, Pia Luise Roppert, Kirsten Alexandra Eberhardt, Martha Charlotte Holtfreter, Sabine Stauga, Ansgar Wilhelm Lohse, Stephan Ehrhardt, Ohene Opare‐Sem, Hans Martin Orth, Fred Stephen Sarfo, Christian Drosten, Anna Maria Eis‐Hübinger, Tom Luedde, Dieter Glebe, Jan Felix Drexler, Torsten Feldt   +19 more
wiley   +1 more source

Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3‐Inflammasome Activation in Macrophages

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Utilizing a clinically relevant course of treatment, our study reveals that glucocorticoids protect against the late NLRP3 inflammasome activation regulating the IL‐1β secretion, the processing of GSDM‐D and pyroptosis following signal 2 stimulation. These potent anti‐inflammatory effects are mediated by the activation of GR signaling and the expansion
David Diaz‐Jimenez, Robert H. Oakley, Jackson A. Hoffman, Carl D. Bortner, Fred Lih, Jianying Li, Jason G. Williams, Erica Scappini, Kevin E. Gerrish, Stavros Garantziotis, Trevor K. Archer, John A. Cidlowski   +11 more
wiley   +1 more source

Cholesterol management in US adults with ASCVD in the Family Heart Database® during 2022-23: Current state of care and opportunities for improvement. [PDF]

Am J Prev Cardiol
MacDougall DE, Ferdinand K, Baum SJ, Sperling L, Hartsuff BK, Wilemon KA, Nissen SE.   +6 more
europepmc   +1 more source

Rittinghaus [PDF]

, 2013
Kuß, Erich
core   +1 more source

Design, Synthesis, and Biological Evaluation of Pseudo‐Natural Products Inspired by Aryloctahydroindole Alkaloids

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
Mesembrine alkaloid pseudo‐natural products were synthesized employing a microwave‐assisted Diels–Alder reaction as a key step. Morphological profiling by cell painting revealed compound‐topology‐dependent mitochondrial fragmentation or inhibition of respiration.
Luca C. Greiner, Freddy A. Bernal, Sasikala Thavam, Maite Brachthäuser, Sonja Sievers, Slava Ziegler, Herbert Waldmann   +6 more
wiley   +1 more source

Author Correction: Adipose tissue retains an epigenetic memory of obesity after weight loss. [PDF]

Nature
Hinte LC, Castellano-Castillo D, Ghosh A, Melrose K, Gasser E, Noé F, Massier L, Dong H, Sun W, Hoffmann A, Wolfrum C, Rydén M, Mejhert N, Blüher M, von Meyenn F.   +14 more
europepmc   +1 more source

Diameter Dependence of Light Absorption in GaAs Nanowires Evidenced by Photoluminescence Spectroscopy

Advanced Optical Materials, Volume 14, Issue 5, 2 February 2026.
Photoluminescence spectroscopy is introduced as a qualitative method to probe light absorption in highly phase‐pure GaAs nanowire arrays and single nanowires, for which direct absorption measurements are challenging. Using defect‐line saturation and the exciton‐to‐plasma transition as indicators for the density of photogenerated charge carriers, a ...
Francisca Marín, Ijaas Mohamed, Oliver Brandt, Lutz Geelhaar   +3 more
wiley   +1 more source

Female condom use among adolescent girls and young women in sub-Saharan Africa: a scoping review protocol investigating availability and consistent use factors. [PDF]

BMJ Open
Moki-Suh B, Mukumbang FC, Krause A, Alison WB.   +3 more
europepmc   +1 more source

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 502-510, February 2026.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio, Huijie Yuan, Leandro Raul Soria, Sara Basse Hansen, Iolanda Boffa, Paola Arena, Benedetta Attianese, Maureen. O'Sullivan, Noelle Cullinan, Lewis Pang, Daan Marinus Ferdinand van Aalten, Nicola Brunetti‐Pierri, Sally Ann Lynch   +12 more
wiley   +1 more source

Short- and long-term complications after slowly resorbable biosynthetic P4HB mesh (Phasix) implantation in European centres: a protocol paper for a multiregistry study. [PDF]

BMJ Open
van den Berg R, Wieser M, Jeekel J, Stabilini C, Bueno-Lledó J, Köckerling F, Chatzimavroudis G, Jørgensen LN, Romain B, PRS Group (Phasix Research Study Group).   +9 more
europepmc   +1 more source