Results 21 to 30 of about 161,749 (270)

Implementation of a combined CDK inhibition and arginine-deprivation approach to target arginine-auxotrophic glioblastoma multiforme cells

open access: yesCell Death and Disease, 2022
The complex effects of combined CDki/SPyADI application on arginine-auxotrophic glioblastoma multiforme cells. CDki/SPyADI combination therapy impairs cell proliferation, invasiveness, gene expression, induces mitochondrial impairment, and vacuole ...
Christin Riess   +15 more
doaj   +1 more source

Auxilium et consilium dans la Chronica regum Castellae

open access: yesE-Spania, 2008
La Chronica regum Castellae présente un modèle de dépendance personnelle fondé sur les devoirs d’auxilium et de consilium, auxquels sont associées des valeurs telles que la strenuitas, la fidelitas et la prudentia.
Patricia Rochwert-Zuili
doaj   +1 more source

Étude comparée du Liber Judiciorum et du Fuero Juzgo

open access: yesE-Spania, 2009
Étant donné sa situation géographique, entre l’Europe et le monde arable, la Castille a joué un rôle particulièrement important, au Moyen Âge, dans le cadre des activités de traduction - notamment avec la célèbre École de Tolède ou les ateliers d ...
Estelle MAINTIER-VERMOREL
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Jerónimo Grimaldi, enviado extraordinario de la república de Génova en Madrid

open access: yesEspacio, Tiempo y Forma. Serie IV, Historia Moderna, 2013
Jerónimo Grimaldi y Pallavicini, embajador de España durante los reinados de Felipe V, Fernando VI y Carlos III y responsable de la primera secretaria de Estado y de Despacho entre 1763 y 1776, es una figura relativamente ausente de la investigación ...
Paulino García Diego
doaj   +1 more source

Responsibility Effects in Decision Making under Risk [PDF]

open access: yes, 2010
We systematically explore decision situations in which a decision maker bears responsibility for somebody else's outcomes as well as for her own in situations of payoff equality.
Pahlke, Julius   +2 more
core   +2 more sources

Clean Up Behind You ‐ Novel Patterning Approach for Solid Immersion Lenses

open access: yesAdvanced Functional Materials, EarlyView.
A focused ion beam (FIB) milling strategy enables rapid fabrication of solid immersion lenses (SILs) with smooth, debris‐free surfaces eliminating the need for post‐processing. The optimized pattern improves efficiency and surface quality. SILs containing NV centers are also investigated, confirming the technique's suitability for quantum and photonic ...
Aleksei Tsarapkin   +10 more
wiley   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

La diplomacia del heredero en Castilla

open access: yesMedievalista
Alfonso X was, while he was crown prince, politically active. It is known that he carried out important activities alongside his father. This article analyses his use of diplomacy in these activities.
Óscar Villarroel González
doaj   +1 more source

Juan Gálvez y Leandro Fernández de Moratín : cuatro escenas, obra de Gálvez, inspiradas en las comedias de Moratín

open access: yesEspacio, Tiempo y Forma. Serie VII, Historia del Arte, 1999
Este artículo analiza los cuatro lienzos ejecutados por Juan Gálvez (1774-1847) destinados a ilustrar la edición de las obras del dramaturgo Leandro Fernández de Moratín, publicadas por la Real Academia de la Historia, en 1830.
Juan Martínez Cuesta
doaj   +1 more source

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