Results 11 to 20 of about 850 (67)

Mucor in a Viral Land: A Tale of Two Pathogens

open access: yesIndian Journal of Ophthalmology, 2021
Purpose: COVID-19 infection, its treatment, resultant immunosuppression, and pre-existing comorbidities have made patients vulnerable to secondary infections including mucormycosis.
M. Sen   +4 more
semanticscholar   +1 more source

Base editing in human cells with monomeric DddA-TALE fusion deaminases

open access: yesNature Communications, 2022
Inter-bacterial toxin DddA-derived cytosine base editors (DdCBEs) enable targeted C-to-T conversions in nuclear and organellar DNA. DddAtox, the deaminase catalytic domain derived from Burkholderia cenocepacia, is split into two inactive halves to avoid ...
Young Geun Mok   +6 more
semanticscholar   +1 more source

TALE-induced immunity against the bacterial blight pathogen Xanthomonas oryzae pv. oryzae in rice

open access: yesPhytopathology Research, 2022
Transcription activator-like effectors (TALEs) are proteins produced by plant pathogenic Xanthomonas spp. TALEs exhibit a conserved structure and have the ability to directly bind to the promoter region of host target genes where they activate ...
Xiameng Xu   +8 more
semanticscholar   +1 more source

Identification of TALE Transcription Factor Family and Expression Patterns Related to Fruit Chloroplast Development in Tomato (Solanum lycopersicum L.)

open access: yesInternational Journal of Molecular Sciences, 2022
The TALE gene family is an important transcription factor family that regulates meristem formation, organ morphogenesis, signal transduction, and fruit development. A total of 24 genes of the TALE family were identified and analyzed in tomato.
Jin Wang   +15 more
semanticscholar   +1 more source

The TALE never ends: A comprehensive overview of the role of PBX1, a TALE transcription factor, in human developmental defects

open access: yesHuman Mutation, 2022
PBX1 is a highly conserved atypical homeodomain transcription factor (TF) belonging to the TALE (three amino acid loop extension) family. Dimerized with other TALE proteins, it can interact with numerous partners and reach dozens of regulating sequences,
L. Mary   +4 more
semanticscholar   +1 more source

Gamete expression of TALE class HD genes activates the diploid sporophyte program in Marchantia polymorpha

open access: yeseLife, 2021
Eukaryotic life cycles alternate between haploid and diploid phases and in phylogenetically diverse unicellular eukaryotes, expression of paralogous homeodomain genes in gametes primes the haploid-to-diploid transition.
Tom Dierschke   +5 more
semanticscholar   +1 more source

The Cosmic-Ray Composition between 2 PeV and 2 EeV Observed with the TALE Detector in Monocular Mode [PDF]

open access: yesAstrophysical Journal, 2020
We report on a measurement of the cosmic-ray composition by the Telescope Array Low-energy Extension (TALE) air fluorescence detector (FD). By making use of the Cherenkov light signal in addition to air fluorescence light from cosmic-ray (CR)-induced ...
R. Abbasi   +146 more
semanticscholar   +1 more source

Genome-Wide Identification and Characterization of TALE Superfamily Genes in Soybean (Glycine max L.)

open access: yesInternational Journal of Molecular Sciences, 2021
The three-amino-acid-loop-extension (TALE) superfamily genes broadly existed in plants, which played important roles in plant growth, development and abiotic stress responses. In this study, we identified 68 Glycine max TALE (GmTALE) superfamily members.
Liang Wang   +3 more
semanticscholar   +1 more source

Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma

open access: yesPLoS ONE, 2021
Homeobox genes encode transcription factors which regulate basic processes in development and cell differentiation and are grouped into classes and subclasses according to sequence similarities.
S. Nagel   +4 more
semanticscholar   +1 more source

TALE: Transformer-based protein function Annotation with joint sequence–Label Embedding

open access: yesbioRxiv, 2020
Motivation Facing the increasing gap between high-throughput sequence data and limited functional insights, computational protein function annotation provides a high-throughput alternative to experimental approaches.
Yue Cao, Yang Shen
semanticscholar   +1 more source

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