Results 1 to 10 of about 215,309 (173)

Nanomechanical Study of Enzyme: Coenzyme Complexes: Bipartite Sites in Plastidic Ferredoxin-NADP⁺ Reductase for the Interaction with NADP. [PDF]

Antioxidants (Basel), 2022
Plastidic ferredoxin-NADP+ reductase (FNR) transfers two electrons from two ferredoxin or flavodoxin molecules to NADP+, generating NADPH. The forces holding the Anabaena FNR:NADP+ complex were analyzed by dynamic force spectroscopy, using WT FNR and ...
Pérez-Domínguez S, Caballero-Mancebo S, Marcuello C, Martínez-Júlvez M, Medina M, Lostao A.   +5 more
europepmc   +2 more sources

Biohybrid photosynthetic charge accumulation detected by flavin semiquinone formation in ferredoxin-NADP⁺ reductase. [PDF]

Chem Sci, 2022
Flavin chemistry is ubiquitous in biological systems with flavoproteins engaged in important redox reactions. In photosynthesis, flavin cofactors are used as electron donors/acceptors to facilitate charge transfer and accumulation for ultimate use in ...
Utschig LM, Brahmachari U, Mulfort KL, Niklas J, Poluektov OG.   +4 more
europepmc   +2 more sources

Tethering ferredoxin-NADP+ reductase to photosystem I promotes photosynthetic cyclic electron transfer. [PDF]

Plant Cell
Fixing CO2 via photosynthesis requires ATP and NADPH. Linear electron transfer (LET) supplies both metabolites, yet depending on environmental conditions, additional ATP is required which can be generated by cyclic electron transfer (CET).
Emrich-Mills TZ, Proctor MS, Degen GE, Jackson PJ, Richardson KH, Hawkings FR, Buchert F, Hitchcock A, Hunter CN, Mackinder LCM, Hippler M, Johnson MP.   +11 more
europepmc   +2 more sources

Redox-dependent hydrogen-bond network rearrangement of ferredoxin-NADP⁺ reductase revealed by high-resolution X-ray and neutron crystallography. [PDF]

Acta Crystallogr F Struct Biol Commun
High-resolution X-ray and neutron crystallography reveal redox-dependent rearrangements in the hydrogen-bond network of ferredoxin–NADP+ reductase (FNR), highlighting structural changes around the FAD cofactor and shifts in water molecules that underpin ...
Uenaka M, Ohnishi Y, Ise A, Yu J, Yano N, Kusaka K, Tanaka H, Kurisu G.   +7 more
europepmc   +2 more sources

A bacterial effector protein targets plant ferredoxin-NADP+ reductase to promote infection. [PDF]

PLoS Pathog
Pathogenic bacteria utilize a type III secretion system to translocate effector proteins into plant cells, where they inhibit plant immunity or interfere with normal cellular functions to facilitate infection.
Wang L, Liu X, Yu F, Pu W, Li X, Wu D.
europepmc   +2 more sources

NADP(H) allosterically regulates the interaction between ferredoxin and ferredoxin-NADP⁺ reductase. [PDF]

FEBS Open Bio, 2019
Ferredoxin‐NADP+ reductase (FNR) in plants receives electrons from ferredoxin (Fd) at the end of the photosynthetic electron transfer chain and converts NADP+ to NADPH. The interaction between Fd and FNR in plants was previously shown to be attenuated by
Kimata-Ariga Y, Chikuma Y, Saitoh T, Miyata M, Yanagihara Y, Yamane K, Hase T.   +6 more
europepmc   +2 more sources

The FinR-regulated essential gene fprA, encoding ferredoxin NADP+ reductase: Roles in superoxide-mediated stress protection and virulence of Pseudomonas aeruginosa. [PDF]

PLoS One, 2017
Pseudomonas aeruginosa has two genes encoding ferredoxin NADP(+) reductases, denoted fprA and fprB. We show here that P. aeruginosa fprA is an essential gene.
Boonma S, Romsang A, Duang-Nkern J, Atichartpongkul S, Trinachartvanit W, Vattanaviboon P, Mongkolsuk S.   +6 more
europepmc   +2 more sources

Biosynthesis of Orthogonal Molecules Using Ferredoxin and Ferredoxin-NADP⁺ Reductase Systems Enables Genetically Encoded PhyB Optogenetics. [PDF]

ACS Synth Biol, 2018
Transplanting metabolic reactions from one species into another has many uses as a research tool with applications ranging from optogenetics to crop production.
Kyriakakis P, Catanho M, Hoffner N, Thavarajah W, Hu VJ, Chao SS, Hsu A, Pham V, Naghavian L, Dozier LE, Patrick GN, Coleman TP.   +11 more
europepmc   +2 more sources

Identification of Inhibitors Targeting Ferredoxin-NADP⁺ Reductase from the Xanthomonas citri subsp. citri Phytopathogenic Bacteria. [PDF]

Molecules, 2017
Ferredoxin-NADP(H) reductases (FNRs) deliver NADPH or low potential one-electron donors to redox-based metabolism in plastids and bacteria. Xanthomonas citri subsp.
Martínez-Júlvez M, Goñi G, Pérez-Amigot D, Laplaza R, Ionescu IA, Petrocelli S, Tondo ML, Sancho J, Orellano EG, Medina M.   +9 more
europepmc   +2 more sources

Inhibitory Activity and Docking Analysis of Antimalarial Agents from Stemona sp. toward Ferredoxin-NADP+ Reductase from Malaria Parasites. [PDF]

J Parasitol Res, 2018
Ferredoxin-NADP+ reductases (FNRs, EC 1.18.1.2) were found in the plastids of Plasmodium and have been considered as a target for the development of new antimalarial agents.
Pudjiastuti P, Puspaningsih NNT, Siswanto I, Fanani MZ, Ariga YK, Hase T, Sarker SD, Nahar L.   +7 more
europepmc   +2 more sources