Results 31 to 40 of about 18,518 (194)

Metagenomic analysis of the ferret fecal viral flora.

PLoS ONE, 2013
Ferrets are widely used as a small animal model for a number of viral infections, including influenza A virus and SARS coronavirus. To further analyze the microbiological status of ferrets, their fecal viral flora was studied using a metagenomics ...
Saskia L Smits, V Stalin Raj, Minoushka D Oduber, Claudia M E Schapendonk, Rogier Bodewes, Lisette Provacia, Koert J Stittelaar, Albert D M E Osterhaus, Bart L Haagmans   +8 more
doaj   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Affecting the Properties of Copper–Graphene Electroconductive Composite by Severe Plastic Deformation

Advanced Engineering Materials, EarlyView.
Copper‐based composites enhanced with carbon feature convenient mechanical properties and favorable electric conductivity. Processing via deformation and thermomechanical treatments can introduce advantageous microstructures further enhancing their performance. Herein, copper–graphene powder‐based composites are directly consolidated via rotary swaging
Radim Kocich, Lenka Kunčická, Pavel Czernek, Zifan Wang   +3 more
wiley   +1 more source

Diabetes mellitus em furões (Mustela putorius furo)

Pubvet
Os furões vêm ganhando popularidade como animais de companhia, o que tem despertado maior interesse da medicina veterinária por suas doenças, incluindo o diabetes mellitus (DM). No Brasil, sua importação é regulamentada pelo Instituto Brasileiro do Meio
Angela Akamatsu, Camila de Oliveira Scarpel, Matheus Nemer Albergaria Parket   +2 more
doaj   +1 more source

Characterization of young and aged ferrets as animal models for SARS-CoV-2 infection with focus on neutrophil extracellular traps

Frontiers in Immunology, 2023
Neutrophil extracellular traps (NETs) are net-like structures released by activated neutrophils upon infection [e.g., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] as part of the innate immune response that have protective effects by ...
Veronika Pilchová, Veronika Pilchová, Ingo Gerhauser, Ingo Gerhauser, Federico Armando, Katrin Wirz, Katrin Wirz, Tom Schreiner, Tom Schreiner, Nicole de Buhr, Nicole de Buhr, Gülşah Gabriel, Gülşah Gabriel, Kerstin Wernike, Donata Hoffmann, Martin Beer, Wolfgang Baumgärtner, Wolfgang Baumgärtner, Maren von Köckritz-Blickwede, Maren von Köckritz-Blickwede, Claudia Schulz   +20 more
doaj   +1 more source

Advanced Electron Microscopy and Microcomputed Tomography Analysis of Single‐Crystal Ni‐Base Superalloys After Short‐Term Multiaxial Creep

Advanced Engineering Materials, EarlyView.
This work studies the anisotropic behavior of circular notched tensile specimens of Ni‐base superalloy single crystals during high‐temperature tensile creep along [001], [110], and [111]. Correlative scale‐bridging imaging of specimens reveals early rupture along [110] because 1) plastic deformation proceeds faster at notch center; 2) more (brittle ...
Leonardo Agudo Jácome, Lijie Cao, Christoph Somsen, Johannes Boes, René Hesse, Werner Theisen, Gunther Eggeler   +6 more
wiley   +1 more source

Mycoplasmosis in Ferrets

Emerging Infectious Diseases, 2012
We report an outbreak of severe respiratory disease associated with a novel Mycoplasma species in ferrets. During 2009-2012, a respiratory disease characterized by nonproductive coughing affected ≈8,000 ferrets, 6-8 weeks of age, which had been imported from a breeding facility in Canada. Almost 95% became ill, but almost none died.
Matti Kiupel, Danielle R. Desjardins, Ailam Lim, Carole Bolin, Cathy A. Johnson-Delaney, James H. Resau, Michael M. Garner, Steven R. Bolin   +7 more
openaire   +3 more sources

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

Influenza virus immune imprinting dictates the clinical outcomes in ferrets challenged with highly pathogenic avian influenza virus H5N1

Frontiers in Veterinary Science, 2023
Zoonotic transmission of H5N1 highly pathogenic avian influenza virus (HPAIV) into the human population is an increasing global threat. The recent 2022 HPAIV outbreak significantly highlighted this possibility, increasing concern in the general ...
Ivette A. Nuñez, Ivette A. Nuñez, Hyesun Jang, Ying Huang, Alyson Kelvin, Ted M. Ross, Ted M. Ross   +6 more
doaj   +1 more source

Descriptive, comparative, and functional anatomy of the facial musculature in cattle (Bos taurus)

The Anatomical Record, EarlyView.
Abstract Facial expressions can provide insight into animal emotions and pain, but no standardized system for assessing the entire facial display in cattle (Bos taurus Linnaeus) exists. The Facial Action Coding System (FACS), originally developed for humans, identifies distinct facial movements based on mimetic muscles.
Maja Söderlind, Bridget Cain, Katrina Ask, Jean‐Francois Valarcher, Elin Hernlund, Pia Haubro Andersen, Marie Rhodin   +6 more
wiley   +1 more source