Results 151 to 160 of about 282,390 (323)
Advanced Science, EarlyView.This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan +16 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang +15 more
wiley +1 more source
, 2010 Screen-printed platinum electrodes developed for use in corrosion monitoring applications have been used to detect cupric and ferric ions both individually and as mixtures in a background of 3.5% by weight sodium chloride and in the presence of dissolved
Cranny, Andrew +6 more
core
Advanced Science, EarlyView.This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong +15 more
wiley +1 more source
Advanced Science, EarlyView.Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan +11 more
wiley +1 more source
Erratum for Fang and Casadevall, Research Funding: the Case for a Modified Lottery
mBio, 2016 Ferric C. Fang, Arturo Casadevall
doaj +1 more source
Advanced Science, EarlyView.The Prussian Blue Analogue molecular magnet KMnFeHCF is demonstrated as a high‐performance cathode for ultra‐fast aqueous ammonium‐ion batteries. A full cell using KMnFeHCF and graphite delivers ~71 mAh g−1 at 1.25 A g−1 and ~51 mAh g−1 at 2.2 A g−1, retaining 50% capacity after 1850 cycles. Its scalability, cycling stability, and low cost offer strong
Nilasha Maiti +5 more
wiley +1 more source
Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
Advanced Science, EarlyView.The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source