Results 131 to 140 of about 101,690 (303)

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

Synthesis, Cytotoxicity and Antioxidant Activity Evaluation of Some Thiazolyl–Catechol Compounds

Antioxidants
A series of thiazolyl–catechol compounds with antioxidant and cytotoxic activities were synthesized by a Hantzsch heterocyclization, using diverse thioamides as the thiocarbonyl component and 4-chloroacetyl-catechol as haloketone.
Alexandra Cătălina Cornea, Gabriel Marc, Ioana Ionuț, Cristina Moldovan, Ionel Fizeșan, Andreea-Elena Petru, Ionuț-Valentin Creștin, Adrian Pîrnău, Laurian Vlase, Ovidiu Oniga   +9 more
doaj   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

Confirmation of nitro compounds by ferrous dimethylglyoxime

BUNSEKI KAGAKU, 1972
Isamu TSUBAKI, Tsutomu NAKANISHI
openaire   +2 more sources

Rapid Steam‐Assisted Temperature Swing Adsorption for Direct Air Capture Using a Rotary Adsorber

Advanced Science, EarlyView.
This study presents a direct air capture (DAC) device based on a steam‐regeneration rotary adsorber for high‐purity CO2. Testing of the prototype demonstrates its capability for continuous and stable carbon capture with the potential to achieve ton‐scale.
Junye Wu, Yunhao Chen, Kuihua Wang, Yingjie Huo, Yanlin Chen, Quanwen Pan, Tianshu Ge   +6 more
wiley   +1 more source

Evaluation study on gas-phase passivation inhibiting the spontaneous combustion tendency of ferrous sulfide compounds

Scientific Reports
The iron sulfide compound FeS, present in petrochemical plants, is prone to spontaneous combustion when exposed to air, posing a significant threat to the safety of production processes in the petrochemical industry.
Yuanyuan Zhang, HaSung Kong, Ruixuan Hao, Qin Xu, Long Zhao   +4 more
doaj   +1 more source

Enhancing sustainable silk Textiles: Optimization of teak leaf extract dyeing and antibacterial efficacy

Current Research in Green and Sustainable Chemistry
This study introduces an environmentally friendly method for dyeing silk using pigments extracted from young teak leaves (Tectona grandis L.), offering a sustainable solution to reduce pollution from synthetic dyes while repurposing agricultural waste ...
Nattadon Rungruangkitkrai, Rattanaphol Mongkholrattanasit, Peeraya Ounu, Nawarat Chartvivatpornchai, Jirachaya Boonyarit, Kamlai Laohaphatanaleart, Rungsima Chollakup   +6 more
doaj   +1 more source

A Laminating Strategy to Manyfold Enhance the Elastic Stretchability of Stretchable Electronics

Advanced Science, EarlyView.
We propose a laminating strategy that laminates a thick‐polymer layer onto the thin‐ribbon metallic structure. Using serpentine structures on soft and hard substrates as representative cases, this approach increases elastic stretchability by 3.5‐fold and 2.3‐fold.
Zanxin Zhou, Xiaolei Wu, Xinkai Xu, Fanming Wang, Shuang Li, Huiling Li, Yewang Su   +6 more
wiley   +1 more source

BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression

Advanced Science, EarlyView.
BZW1 attenuates ferroptosis by competitively binding NCOA4 and suppress ferrtinophagy‐mediated iron release. The depletion of BZW1 triggers lipid peroxidation through iron homeostasis. Extracellularly, BZW1 attenuates immunogenic cell death and reinvigorates cytotoxic T‐cell responses.
Linyao Zhao, Yue Peng, Qing Liang, Shi Liu, Yang Li, Lei Ma, Menghan Hu, Sujuan Zheng, Zhihua Liu, Shugeng Gao   +9 more
wiley   +1 more source