Results 141 to 150 of about 123,874 (333)

Life cycle assessment of Swiss organic farming systems [PDF]

open access: yes, 2006
The impacts of organic and integrated farming systems in Switzerland on the environment have been assessed in a comprehensive study by the life cycle assessment method. This paper reports a comparison of the treatments of the DOC experiment.
Dubois, D   +3 more
core  

Systematic Targeting of GD2‐Positive Neuroblastoma Tumors With a Photooncolytic Phage Nanovector Platform

open access: yesAdvanced Science, EarlyView.
A tumor‐penetrating photooncolytic phage is developed for selectively targeting and delivering photosensitizers to GD2‐positive Neuroblastoma cells. Upon light activation, it precisely induces oncolysis of GD2‐positive cells with no effect on GD2‐negative ones.
Suleman Khan Zadran   +25 more
wiley   +1 more source

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

open access: yesAdvanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen   +16 more
wiley   +1 more source

Mineral nutrition and its genetic signature in oil palm (Elaeis guineensis Jacq.): A possible panorama for high yielding materials at low fertiliser cost [PDF]

open access: yes, 2010
Significant differences in the mineral nutrition have been demonstrated between progenies and the main categories at PT Socfindo (Jacquemard et al, 2002). A new set of investigations has been conducted based on a larger genetic background.
Jacquemard, Jean-Charles   +4 more
core  

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

open access: yesAdvanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li   +24 more
wiley   +1 more source

Fertilisation of the Hazel [PDF]

open access: yesNature, 1871
IN NATURE for April 7, 1870 (vol. i. p. 583), Mr. Marcus Hartog stated, as the result of his observations, that the male catkins and female flowers of the hazel are not simultaneously developed on the same twig, and that therefore a kind of quasi-cross-fertilisation necessarily takes place.
openaire   +1 more source

Soil nitrate N as influenced by annually undersown cover crops in spring cereals [PDF]

open access: yes, 2003
Cover crops can reduce leaching and erosion, introduce variability into crop rotations and fix nitrogen (N) for use by the main crops. In Finland, undersowing is a suitable method for establishing cover crops in cereals.
Eriksson, Christian   +3 more
core  

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

open access: yesAdvanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui   +6 more
wiley   +1 more source

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