Results 171 to 180 of about 49,503 (303)

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

Advanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge, John S. Fossey, David Gonzalez Calatayud, Stephen E. Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand, Stanley W. Botchway, David Gurevich, Tony D. James, Sofia I. Pascu   +13 more
wiley   +1 more source

Understanding and Regulating C–N Coupling Pathways for Electrocatalytic Urea Synthesis From CO2 and NO3−/NO2−

Advanced Science, EarlyView.
Understanding and regulating C–N coupling is central to electrocatalytic urea synthesis from CO2 and NO3−/NO2−. This review outlines representative coupling pathways, summarizes carbon‐ and nitrogen‐side intermediate regulation strategies, and highlights in situ/operando tools for mechanistic clarification and catalyst design. ABSTRACT Electrocatalytic
Xingbao Chen, Zhuo Li, Lebin Cai, Paul Kilmartin, Bao Yu Xia, Ziyun Wang   +5 more
wiley   +1 more source

Sperm Imprinted Gene Methylation and DNA Fragmentation in ICSI Outcomes: A Pilot Study. [PDF]

Epigenomes
Conflitti AC, Konstantinidou F, Buonacquisto A, Cicolani G, Delli Paoli E, Di Chiano S, Linari A, Muzii L, Bianchini S, Quaranta F, Pallotti F, Lombardo F, Stuppia L, Gatta V, Paoli D.   +14 more
europepmc   +1 more source

Optimum N fertilisation: balancing fertilisation and N losses in dairy systems

, 2017
A simulation study was carried out to investigate the effects on nitrogen (N) losses in dairy farming when fertilisation rates are targeted to achieve high pasture yields.
Brittany Paton (15398438), Rogerio Cichota (15394187), Armin Werner (6942521), Iris Vogeler (15394622), Jason Trethewey (15394670)   +4 more
core  

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Multicentre randomised comparative effectiveness trial of cleavage-stage versus blastocyst-stage embryo transfer in patients with few embryos (PRECISE): implementation of a study protocol in reproductive medicine. [PDF]

BMJ Open
Neuhausser WM, Vaughan DA, Sakkas D, Penzias A, Anchan RM, Hornstein MD, Reeder HT, Barnhart KT, Stewart EA, Cedars M, Halicigil C, Taylor HS, Beck M, Hacker MR, Marsh E, Gracia CR, Rosenwaks Z, Williams Z, Rabideau DJ, Steering Committee and Study Investigators of the PRECISE Trial, Executive Committee and Study Investigators of the PRECISE Trial, Protocol Committee and Study Investigators of the PRECISE Trial, Stakeholder Advisory Group and Study Investigators of the PRECISE Trial, Data and Safety Monitoring Board and Study Investigators of the PRECISE Trial, Communications and Branding Committee and Study Investigators of the PRECISE Trial, Publication Committee and Study Investigators of the PRECISE Trial.   +25 more
europepmc   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

Advanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao, Ting‐Yu Han, Yan‐Li Cheng, Yi‐Dan Zhang, Yu‐Wei Zhang, JinJian Guo, ShaoJun Zhang, WenZe Huang, Jing Zhang, Pei‐Yu Liao, Ying Xin, ChuanChen Chu, Qing‐Yuan Sun, ZhiZhen Liu, Xiang‐Hong Ou, Jun Xie   +15 more
wiley   +1 more source

Agronomic Biofortification Strategies to Increase Grain Zinc Concentrations of Wheat, Rice and Maize: A Systematic Review and Network-Meta-Analysis. [PDF]

Campbell Syst Rev
Domingos IFN, Baranski M, Rengel Z, Bilsborrow P, Stewart G.   +4 more
europepmc   +1 more source

Interfacial Tandem Catalysis Over a CuSn(OH)6/Co Heterostructure Enables Efficient Electroreduction of Nitrate to Ammonia

Advanced Science, EarlyView.
Interfacial tandem catalysis is developed for efficient electrochemical reduction of NO3− to NH3 over a CuSn(OH)6/Co heterostructure. CuSn(OH)6 accelerates the rate‐determining NO3−‐to‐*NO2 conversion, whereas Co promotes H2O dissociation to enhance *H supply for the rapid hydrogenation of *NO2 intermediate to NH3.
Yuan‐Yuan Hei, Qing Chen, Jie Gu, Yifan Leng, Yaping Huang, Sunhui Chen, Hong Sun, Hongfang Du   +7 more
wiley   +1 more source

Appraisal of a Hypothesis on Embryo Fusion and Individuation. [PDF]

Biology (Basel)
O'Keeffe FJ, Mendz GL.
europepmc   +1 more source